Duchenne muscular dystrophy is a highly progressive muscle wasting disorder due to
primary abnormalities in one of the largest genes in the human genome, the DMD gene …

The X-linked muscle-wasting disease Duchenne muscular dystrophy is caused by mutations
in the gene encoding dystrophin. There is currently no effective treatment for the disease; …

Duchenne muscular dystrophy is a very severe disease which affects the skeletal
musculature in human patients. It produces muscle wasting. Necrotic fibres are partially …

The membrane cytoskeletal component dystrophin and its associated glycoproteins play a
central role in the molecular pathogenesis of several muscular dystrophies, ie …

Duchenne muscular dystrophy (DMD) is a severe, progressive, muscle-wasting disease,
characterized by progressive deterioration of skeletal muscle that causes rapid loss of …

The X-linked muscle wasting disease Duchenne muscular dystrophy is caused by the lack of
dystrophin in muscle. Protein structure predictions, patient mutations, in vitro binding studies …

Duchenne muscular dystrophy (DMD) is the most prevalent and severe form of human
muscular dystrophy. While clinical descriptions of DMD date back to the 1850's, over 100 …

Background Dystrophin is a rod-shaped cytoplasmic protein that provides sarcolemmal
stability as a structural link between the cytoskeleton and the extracellular matrix via the …

The X‐linked inherited neuromuscular disorder Duchenne muscular dystrophy is
characterised by primary abnormalities in the membrane cytoskeletal component dystrophin …

Mutations in the dystrophin gene lead to dystrophin deficiency, which is the cause of
Duchenne muscular dystrophy (DMD). This important discovery more than 10 years ago …