A genome-wide Epstein-Barr virus polyadenylation map and its antisense RNA to EBNA

V Majerciak, W Yang, J Zheng, J Zhu… - Journal of virology, 2019 - Am Soc Microbiol
Epstein-Barr virus (EBV) is a ubiquitous human pathogen associated with Burkitt's
lymphoma and nasopharyngeal carcinoma. Although the EBV genome harbors more than a …

Epstein–Barr virus: a master epigenetic manipulator

RS Scott - Current opinion in virology, 2017 - Elsevier
Highlights•EBV encodes viral epigenetic effectors that alter viral and host epigenomes.•EBV-
induced epigenetic changes to the host epigenome have oncogenic consequences.• …

Global bidirectional transcription of the Epstein-Barr virus genome during reactivation

T O'Grady, S Cao, MJ Strong, M Concha… - Journal of …, 2014 - Am Soc Microbiol
Epstein-Barr virus (EBV) reactivation involves the ordered induction of approximately 90
viral genes that participate in the generation of infectious virions. Using strand-specific RNA …

Epigenetic Mechanisms in Latent Epstein-Barr Virus Infection and Associated Cancers

AS Torne, ES Robertson - Cancers, 2024 - mdpi.com
Simple Summary Epstein–Barr virus (EBV) was first isolated in 1964 and has since become
an important human tumor virus. With an estimated 90% of the human population infected …

Phosphorylation sites of Epstein–Barr Virus EBNA1 regulate its function

SJ Duellman, KL Thompson… - Journal of general …, 2009 - microbiologyresearch.org
Epstein–Barr virus (EBV) is the causative agent of infectious mononucleosis and a risk factor
for developing a variety of lymphomas and carcinomas. EBV nuclear antigen 1 (EBNA1) is …

An epigenetic journey: Epstein-Barr virus transcribes chromatinized and subsequently unchromatinized templates during its lytic cycle

A Chakravorty, B Sugden, EC Johannsen - Journal of virology, 2019 - Am Soc Microbiol
ABSTRACT The Epstein-Barr virus (EBV) lytic phase, like those of all herpesviruses,
proceeds via an orderly cascade that integrates DNA replication and gene expression. EBV …

[HTML][HTML] Genome-wide transcription program and expression of the Rta responsive gene of Epstein–Barr virus

CC Lu, YY Jeng, CH Tsai, MY Liu, SW Yeh, TY Hsu… - Virology, 2006 - Elsevier
Infection with Epstein–Barr virus (EBV) usually leads to a latent state in B lymphocytes. The
virus can be reactivated through two viral transactivators, Zta and Rta, leading to a cascade …

Features distinguishing Epstein-Barr virus infections of epithelial cells and B cells: viral genome expression, genome maintenance, and genome amplification

C Shannon-Lowe, E Adland, AI Bell… - Journal of …, 2009 - Am Soc Microbiol
Epstein-Barr virus (EBV) is associated with malignant diseases of lymphoid and epithelial
cell origin. The tropism of EBV is due to B-cell-restricted expression of CD21, the major …

Identification of a Novel Promoter Located Within the Bam HI Q Region of the Epstein-Barr Virus Genome for the EBNA 1 Gene

CHINEU TSAI, ST LIU, YUSUN CHANG - DNA and cell biology, 1995 - liebertpub.com
ABSTRACT EBNA 1 is the only antigen expressed in both Epstein-Barr virus (EBV)-infected
nasopharyngeal carcinoma (NPC) and Burkitt's lymphoma cells. Previous studies showed …

Epigenetic dysregulation of the host cell genome in Epstein–Barr virus-associated neoplasia

HH Niller, H Wolf, J Minarovits - Seminars in cancer biology, 2009 - Elsevier
Epstein–Barr virus (EBV), a human herpesvirus, is associated with a wide variety of
malignant tumors. The expression of the latent viral RNAs is under strict, host-cell dependent …