The pathophysiology of ischemic acute renal failure is complex, and the role of leukocyte
adhesion in this process is not well defined. A monoclonal antibody (mAb) against …

Studies in the rat have pointed to a role for intercellular adhesion molecule-1 (ICAM-1) in the
pathogenesis of acute tubular necrosis. These studies used antibodies, which may have …

ICAM-1 has been implicated in the pathophysiology of ischemic-reperfusion injury in a
number of organs, but its role in mediating severe ischemic-reperfusion injury in the kidney …

The Cytokine-adhesion Molecule Cascade in Ischemia/Reperfusion Injury of the Rat Kidney
Page 1 2682 Takada et al. J. Clin. Invest. © The American Society for Clinical Investigation, Inc …

Neutrophils are pivotal in the pathogenesis of reperfusion injury leading to myocardial
infarction. Firm adhesion of PMN to endothelium may be initiated by the interaction between …

The potential role of intercellular adhesion molecule-1 (ICAM-1) in the pathogenesis of
reperfusion injury was investigated in male Fischer rats subjected to 45 min of hepatic …

Ischemia remains the primary cause of acute renal fail-ure in adults. Following the
development and practical application of dialysis, little progress has been made in the …

The involvement of adhesion molecules in the glomerular accumulation of inflammatory
cells and subsequent glomerular injury was examined in WKY rats with nephrotoxic serum …

Adhesion molecules such as intercellular adhesion molecule-1 and vascular cell adhesion
molecule-1 are expressed in the kidney and are regulated by proinflammatory cytokines …

Molecules responsible for adhesion between cells are known to play an important role in the
immune response. The expression of one of these molecules, intercellular adhesion …