[PDF][PDF] Clotting factor genes are associated with preeclampsia in high-altitude pregnant women in the Peruvian Andes

MA Nieves-Colón, KMB Rivera, K Sandoval… - The American Journal of …, 2022 - cell.com
Preeclampsia is a multi-organ complication of pregnancy characterized by sudden
hypertension and proteinuria that is among the leading causes of preterm delivery and …

[HTML][HTML] Genetic variants in preeclampsia: Lessons from studies in Latin-American populations

RT Michita, VL Kaminski, JAB Chies - Frontiers in Physiology, 2018 - frontiersin.org
Placental vascularization is a tightly regulated physiological process in which the maternal
immune system plays a fundamental role. Vascularization of the maternal-placental interface …

[HTML][HTML] Genetic markers for preeclampsia in Peruvian women

J Pacheco-Romero, O Acosta, D Huerta, S Cabrera… - Colombia …, 2021 - scielo.org.co
PACHECO-ROMERO, José et al. Genetic markers for preeclampsia in Peruvian women.
Colomb. Med.[online]. 2021, vol. 52, n. 1, e2014437. Epub Feb 26, 2021. ISSN 1657-9534 …

Genetic risk score for essential hypertension and risk of preeclampsia

CJ Smith, AF Saftlas, CN Spracklen… - American journal of …, 2016 - academic.oup.com
BACKGROUND Preeclampsia is a hypertensive complication of pregnancy characterized by
novel onset of hypertension after 20 weeks gestation, accompanied by proteinuria …

[HTML][HTML] The genetic component of preeclampsia: a whole-exome sequencing study

AT Hansen, JM Bernth Jensen, AM Hvas… - PLoS …, 2018 - journals.plos.org
Preeclampsia is a major cause of maternal and perinatal deaths. The aetiology of
preeclampsia is largely unknown but a polygenetic component is assumed. To explore this …

Genome‐Wide Association Study of Pre‐Eclampsia Detects Novel Maternal Single Nucleotide Polymorphisms and Copy‐Number Variants in Subsets of the …

L Zhao, MB Bracken, AT DeWan - Annals of human genetics, 2013 - Wiley Online Library
A genome‐wide association study was undertaken to identify maternal single nucleotide
polymorphisms (SNPs) and copy‐number variants (CNVs) associated with pre‐eclampsia …

Altered placental ion channel gene expression in preeclamptic high-altitude pregnancies

CG Julian, JA Houck, S Fallahi… - Physiological …, 2023 - journals.physiology.org
High-altitude (> 2,500 m) residence increases the risk of pregnancy vascular disorders such
as fetal growth restriction and preeclampsia, each characterized by impaired placental …

Whole-exome sequencing in multiplex preeclampsia families identifies novel candidate susceptibility genes

PE Melton, MP Johnson, D Gokhale-Agashe… - Journal of …, 2019 - journals.lww.com
Objective: Preeclampsia is a common and serious heritable disorder of human pregnancy.
Although there have been notable successes in identification of maternal susceptibility …

The common single-nucleotide polymorphism rs2681472 is associated with early-onset preeclampsia in Northern Han Chinese women

JP Wan, H Wang, CZ Li, H Zhao, L You… - Reproductive …, 2014 - journals.sagepub.com
Preeclampsia, characterized by hypertension and proteinuria, remains a leading cause of
maternal morbidity and mortality. Recently, a genome-wide association study (GWAS) …

Risk of pre‐eclampsia in patients with a maternal genetic predisposition to common medical conditions: a case–control study

KJ Gray, VP Kovacheva, H Mirzakhani… - … Journal of Obstetrics …, 2021 - Wiley Online Library
Objective To assess whether women with a genetic predisposition to medical conditions
known to increase pre‐eclampsia risk have an increased risk of pre‐eclampsia in …