As an enzyme-free signal amplification strategy, catalytic hairpin assembly (CHA) presents
the advantages of flexible design and high efficiency. Combined with various signal output …

Catalytic hairpin assembly (CHA) with advantages of high efficiency, flexible design, and
mild reaction condition is considered a promising molecular amplifier. Modified working …

Catalytic hairpin assembly (CHA) appears to be a particularly appealing nucleic acid circuit
because of its powerful amplification capability, simple protocols, and enzyme-free and …

Nucleic acids are considered as perfect programmable materials for cascade signal
amplification and not merely as genetic information carriers. Among them, catalytic hairpin …

DNA amplification usually takes place in an aqueous system to facilitate a highly efficient
reaction. Therefore, it is a challenge to connect the DNA amplification with popular dry …

An isothermal, enzyme-free and ultrasensitive protocol for electrochemical detection of DNA
is proposed based on the ingenious combination of target catalyzed hairpin assembly and …

Herein, a nucleic acid assay based on autocatalytic hairpin assembly (ACHA) was
proposed. In this system, two split G-quadruplex sequences were integrated into H1 and H2 …

Nonenzymatic self-assembly circuit utilizing hairpin substrates has been developed to be a
powerful tool for information transduction, amplification and computation. However, the …

Catalytic hairpin assembly (CHA) is an enzyme-free amplification method that it has been
proved to be useful in signal amplification. In this work, hydroxylamine-O-sulfonic acid …

A simple, sensitive, selective, and enzyme-free homogeneous fluorescent biosensing device
for DNA and protein detection is fabricated based on catalytic hairpin assembly (CHA) …