[HTML][HTML] Auraptene has antiviral activity against human coronavirus OC43 in MRC-5 cells

JS Min, YH Jin, S Kwon - Nutrients, 2023 - mdpi.com
Auraptene (7-geranyloxycoumarin) is the abundant prenyloxycoumarin found in the fruits of
Citrus spp. Auraptene has a variety of pharmacological and therapeutic functions, such as …

[HTML][HTML] Natural bis-benzylisoquinoline alkaloids-tetrandrine, fangchinoline, and cepharanthine, inhibit human coronavirus OC43 infection of MRC-5 human lung cells

DE Kim, JS Min, MS Jang, JY Lee, YS Shin, CM Park… - Biomolecules, 2019 - mdpi.com
Stephania tetrandra and other related species of Menispermaceae are the major sources of
the bis-benzylisoquinoline alkaloids tetrandrine (TET), fangchinoline (FAN), and …

[HTML][HTML] Cardamonin as a p38 MAPK signaling pathway activator inhibits human coronavirus OC43 infection in human lung cells

YH Jin, JS Min, S Kwon - Nutrients, 2023 - mdpi.com
A natural chalcone, cardamonin (2′, 4′-dihydroxy-6′-methoxychalcone; CDN) was
isolated from the seeds of Alpinia katsumadai Hayata, which has been traditionally used to …

Aurones: a promising scaffold to inhibit SARS-CoV-2 replication

GS Caleffi, AS Rosa, LG de Souza… - Journal of Natural …, 2023 - ACS Publications
Aurones are a small subgroup of flavonoids in which the basic C6–C3–C6 skeleton is
arranged as (Z)-2-benzylidenebenzofuran-3 (2 H)-one. These compounds are structural …

[HTML][HTML] Antiviral activity of umifenovir in vitro against a broad spectrum of coronaviruses, including the novel SARS-CoV-2 virus

I Leneva, N Kartashova, A Poromov, A Gracheva… - Viruses, 2021 - mdpi.com
An escalating pandemic of the novel SARS-CoV-2 virus is impacting global health, and
effective antivirals are needed. Umifenovir (Arbidol) is an indole-derivative molecule …

[HTML][HTML] The FDA-approved gold drug auranofin inhibits novel coronavirus (SARS-COV-2) replication and attenuates inflammation in human cells

HA Rothan, S Stone, J Natekar, P Kumari, K Arora… - Virology, 2020 - Elsevier
SARS-COV-2 has recently emerged as a new public health threat. Herein, we report that the
FDA-approved drug, auranofin, inhibits SARS-COV-2 replication in human cells at low micro …

[HTML][HTML] Kurarinone inhibits HCoV-OC43 infection by impairing the virus-induced autophagic flux in MRC-5 human lung cells

JS Min, DE Kim, YH Jin, S Kwon - Journal of clinical medicine, 2020 - mdpi.com
Kurarinone is a prenylated flavonone isolated from the roots of Sophora flavescens. Among
its known functions, kurarinone has both anti-apoptotic and anti-inflammatory properties …

[PDF][PDF] Anti-viral effect of usenamine a using SARS-CoV-2 pseudo-typed viruses

Z Li, JE Lee, N Cho, HM Yoo - Heliyon, 2023 - cell.com
The escalating pandemic brought about by the novel SARS-CoV-2 virus is threatening
global health, and thus, it is necessary to develop effective antiviral drugs. Usenamine A is a …

[HTML][HTML] Eupatin, a flavonoid, inhibits coronavirus 3CL protease and replication

YI Park, JH Kim, S Lee, IS Lee, J Park - International Journal of Molecular …, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic has caused more than six million
deaths worldwide since 2019. Although vaccines are available, novel variants of …

[HTML][HTML] Alisol B 23-acetate broadly inhibits coronavirus through blocking virus entry and suppresses proinflammatory T cells responses for the treatment of COVID-19

Q Du, R Liang, M Wu, M Yang, Y Xie, Q Liu… - Journal of Advanced …, 2023 - Elsevier
Introduction Emerging severe acute respiratory syndrome (SARS) coronavirus (CoV)-2
causes a global health disaster and pandemic. Seeking effective anti-pan-CoVs drugs …