[HTML][HTML] Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income
Socioeconomic position (SEP) is a multi-dimensional construct reflecting (and influencing)
multiple socio-cultural, physical, and environmental factors. In a sample of 286,301 …
multiple socio-cultural, physical, and environmental factors. In a sample of 286,301 …
Molecular genetics and economics
The costs of comprehensively genotyping human subjects have fallen to the point where
major funding bodies, even in the social sciences, are beginning to incorporate genetic and …
major funding bodies, even in the social sciences, are beginning to incorporate genetic and …
Genome-wide association study identifies 74 loci associated with educational attainment
Educational attainment is strongly influenced by social and other environmental factors, but
genetic factors are estimated to account for at least 20% of the variation across individuals 1 …
genetic factors are estimated to account for at least 20% of the variation across individuals 1 …
[PDF][PDF] Molecular genetic contributions to social deprivation and household income in UK Biobank
Individuals with lower socio-economic status (SES) are at increased risk of physical and
mental illnesses and tend to die at an earlier age [1–3]. Explanations for the association …
mental illnesses and tend to die at an earlier age [1–3]. Explanations for the association …
[HTML][HTML] Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects
Estimates from genome-wide association studies (GWAS) of unrelated individuals capture
effects of inherited variation (direct effects), demography (population stratification …
effects of inherited variation (direct effects), demography (population stratification …
[HTML][HTML] The sequences of 150,119 genomes in the UK Biobank
BV Halldorsson, HP Eggertsson, KHS Moore… - Nature, 2022 - nature.com
Detailed knowledge of how diversity in the sequence of the human genome affects
phenotypic diversity depends on a comprehensive and reliable characterization of both …
phenotypic diversity depends on a comprehensive and reliable characterization of both …
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment
A genome-wide association study (GWAS) of educational attainment was conducted in a
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
Genome partitioning of genetic variation for complex traits using common SNPs
J Yang, TA Manolio, LR Pasquale, E Boerwinkle… - Nature …, 2011 - nature.com
We estimate and partition genetic variation for height, body mass index (BMI), von
Willebrand factor and QT interval (QTi) using 586,898 SNPs genotyped on 11,586 unrelated …
Willebrand factor and QT interval (QTi) using 586,898 SNPs genotyped on 11,586 unrelated …
[HTML][HTML] Gene discovery and polygenic prediction from a 1.1-million-person GWAS of educational attainment
We conduct a large-scale genetic association analysis of educational attainment in a sample
of~ 1.1 million individuals and identify 1,271 independent genome-wide-significant SNPs …
of~ 1.1 million individuals and identify 1,271 independent genome-wide-significant SNPs …
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Here we conducted a large-scale genetic association analysis of educational attainment in a
sample of approximately 1.1 million individuals and identify 1,271 independent genome …
sample of approximately 1.1 million individuals and identify 1,271 independent genome …