Functional pathophysiology of SARS-CoV-2-induced acute lung injury and clinical implications

NM Habashi, L Camporota… - Journal of applied …, 2021 - journals.physiology.org
The worldwide pandemic caused by the SARS-CoV-2 virus has resulted in over 84,407,000
cases, with over 1,800,000 deaths when this paper was submitted, with comorbidities such …

Mechanical ventilation in COVID‐19: A physiological perspective

JN Cronin, L Camporota, F Formenti - Experimental Physiology, 2022 - Wiley Online Library
New Findings What is the topic of this review? This review presents the fundamental
concepts of respiratory physiology and pathophysiology, with particular reference to lung …

Understanding the pathophysiology of typical acute respiratory distress syndrome and severe COVID-19

L Ball, PL Silva, DR Giacobbe, M Bassetti… - Expert Review of …, 2022 - Taylor & Francis
Introduction Typical acute respiratory distress syndrome (ARDS) and severe coronavirus-19
(COVID-19) pneumonia share complex pathophysiology, a high mortality rate, and an unmet …

Respiratory system mechanics, gas exchange, and outcomes in mechanically ventilated patients with COVID-19-related acute respiratory distress syndrome: a …

MP Reddy, A Subramaniam, C Chua… - The Lancet …, 2022 - thelancet.com
The association of respiratory mechanics, particularly respiratory system static compliance
(C RS), with severity of hypoxaemia in patients with COVID-19-related acute respiratory …

Comparison of COVID-19 induced respiratory failure and typical ARDS: similarities and differences

S Lu, X Huang, R Liu, Y Lan, Y Lei, F Zeng… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a predominantly respiratory infectious disease
caused by novel coronavirus infection (SARS-CoV-2), respiratory failure is the main clinical …

[HTML][HTML] Physiological and biological heterogeneity in COVID-19-associated acute respiratory distress syndrome

LB Ware - The Lancet Respiratory Medicine, 2020 - thelancet.com
One of the most common causes of hospital admission and death in patients with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is acute respiratory …

The respiratory drive: an overlooked tile of COVID-19 pathophysiology

L Gattinoni, JJ Marini, L Camporota - American journal of respiratory …, 2020 - atsjournals.org
Acute respiratory distress syndrome (ARDS) caused by coronavirus disease (COVID-
19)(CARDS) has similarities and differences compared with ARDS from other etiologies (1) …

Pathophysiology of acute respiratory distress syndrome and COVID-19 lung injury

KE Swenson, ER Swenson - Critical care clinics, 2021 - criticalcare.theclinics.com
Acute respiratory distress syndrome (ARDS) is a complex syndrome of acute lung injury
leading to noncardiogenic pulmonary edema from many causes that is heterogenous in its …

Pathophysiology of coronavirus-19 disease acute lung injury

L Camporota, JN Cronin, M Busana… - Current opinion in …, 2022 - journals.lww.com
This review summarises the fundamental pathophysiological features of COVID-19 in the
context of the respiratory system. It provides an overview of the key clinical manifestations of …

Subphenotyping acute respiratory distress syndrome in patients with COVID-19: consequences for ventilator management

LDJ Bos, F Paulus, APJ Vlaar, LFM Beenen… - Annals of the …, 2020 - atsjournals.org
Guidance on the best provision of care for patients with coronavirus disease (COVID-19) is
urgently needed. Recently a strong argument in defense of an evidence-based approach …