Explainable artificial intelligence (XAI) for exploring spatial variability of lung and bronchus cancer (LBC) mortality rates in the contiguous USA

ZU Ahmed, K Sun, M Shelly, L Mu - Scientific reports, 2021 - nature.com
Abstract Machine learning (ML) has demonstrated promise in predicting mortality; however,
understanding spatial variation in risk factor contributions to mortality rate requires …

Hierarchical Bayesian modeling of spatio-temporal patterns of lung cancer incidence risk in Georgia, USA: 2000–2007

P Yin, L Mu, M Madden, JE Vena - Journal of geographical systems, 2014 - Springer
Lung cancer is the second most commonly diagnosed cancer in both men and women in
Georgia, USA. However, the spatio-temporal patterns of lung cancer risk in Georgia have not …

Interpretable machine learning prediction of all-cause mortality

W Qiu, H Chen, AB Dincer, S Lundberg… - Communications …, 2022 - nature.com
Background Unlike linear models which are traditionally used to study all-cause mortality,
complex machine learning models can capture non-linear interrelations and provide …

Machine-learning model to predict the cause of death using a stacking ensemble method for observational data

C Kim, SC You, JM Reps, JY Cheong… - Journal of the …, 2021 - academic.oup.com
Objective Cause of death is used as an important outcome of clinical research; however,
access to cause-of-death data is limited. This study aimed to develop and validate a …

Comprehensive profiling of genomic and transcriptomic differences between risk groups of lung adenocarcinoma and lung squamous cell carcinoma

T Zengin, T Önal-Süzek - Journal of personalized medicine, 2021 - mdpi.com
Lung cancer is the second most frequently diagnosed cancer type and responsible for the
highest number of cancer deaths worldwide. Lung adenocarcinoma (LUAD) and lung …

CGBayesNets: conditional Gaussian Bayesian network learning and inference with mixed discrete and continuous data

MJ McGeachie, HH Chang… - PLoS computational …, 2014 - journals.plos.org
Bayesian Networks (BN) have been a popular predictive modeling formalism in
bioinformatics, but their application in modern genomics has been slowed by an inability to …

Assessing lung cancer absolute risk trajectory based on a polygenic risk model

RJ Hung, MT Warkentin, Y Brhane, N Chatterjee… - Cancer research, 2021 - AACR
Lung cancer is the leading cause of cancer-related death globally. An improved risk
stratification strategy can increase efficiency of low-dose CT (LDCT) screening. Here we …

Predicting the hotspots of age-adjusted mortality rates of lower respiratory infection across the continental United States: Integration of GIS, spatial statistics and …

A Mollalo, B Vahedi, S Bhattarai, LC Hopkins… - International Journal of …, 2020 - Elsevier
Objective Although lower respiratory infections (LRI) are among the leading causes of
mortality in the US, their association with underlying factors and geographic variation have …

Application of machine learning in predicting survival outcomes involving real-world data: a scoping review

Y Huang, J Li, M Li, RR Aparasu - BMC Medical Research Methodology, 2023 - Springer
Background Despite the interest in machine learning (ML) algorithms for analyzing real-
world data (RWD) in healthcare, the use of ML in predicting time-to-event data, a common …

A deep learning-based framework for lung cancer survival analysis with biomarker interpretation

L Cui, H Li, W Hui, S Chen, L Yang, Y Kang, Q Bo… - BMC …, 2020 - Springer
Background Lung cancer is the leading cause of cancer-related deaths in both men and
women in the United States, and it has a much lower five-year survival rate than many other …