The versatility of pluripotent stem cells, attributable to their unlimited self-renewal capacity
and plasticity, has sparked a considerable interest for potential application in regenerative …

Despite advances in cardiovascular biology and medical therapy, heart disorders are the
leading cause of death worldwide. Cell-based regenerative therapies become a promising …

Cardiovascular diseases are the leading cause of morbidity and mortality worldwide.
Regenerative therapy has been applied to restore lost cardiac muscle and cardiac …

Cardiovascular disease is the leading cause of death worldwide and bears an immense
economic burden. Late-stage heart failure often requires total heart transplantation; …

Cardiac muscle has limited proliferative capacity, and regenerative therapies are highly in
demand as a new treatment strategy. Pharmacological and non-pharmacological therapies …

Cardiovascular disease (CVD) continues to be the leading cause of global morbidity and
mortality. Heart failure remains a major contributor to this mortality. Despite major …

Significance: Despite decades of progress in cardiovascular biology and medicine, heart
disease remains the leading cause of death, and there is no cure for the failing heart. Since …

Cardiovascular disease (CVD) is still the leading cause of death worldwide. Coronary artery
occlusion, or myocardial infarction (MI) causes massive loss of cardiomyocytes. The …

Heart regeneration addresses a central problem in cardiology, the irreversibility of the loss of
myocardium that eventually leads to heart failure. True restoration of heart function can only …

Because the heart is a postmitotic organ, cardiomyocytes are in a state of cell cycle arrest.
However, some experiments using the newt and zebrafish have confirmed that the damaged …