Background/Aims: A key issue in neuroendocrine neoplasia management is the
identification of blood signatures that specifically define the activity of a cancer or local tumor …

It is well documented that dysregulation of microRNAs is a hallmark of human cancers. Thus,
this family of small non-coding regulatory molecules represents an excellent source of …

Abstract Background/Aims: Neuroendocrine neoplasms of the small intestine (SI-NENs)
constitute 25-30% of all gastroenteropancreatic NEN. These tumors arise from …

The incidence of neuroendocrine neoplasias (NEN) continues to increase. Since the primary
tumor cannot be diagnosed in some cases of metastatic disease, new biomarkers are clearly …

Novel molecular analytes are needed in small bowel neuroendocrine tumours (SBNETs) to
better determine disease aggressiveness and predict treatment response. In this study, we …

Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) can be challenging to evaluate
histologically. microRNAs (miRNAs) are small RNA molecules that often are excellent …

Background Current diagnostic and prognostic blood-based biomarkers for neuroendocrine
tumors are limited. MiRNAs have tumor-specific expression patterns, are relatively stable …

Objective: To discover serum-based microRNA (miRNA) biomarkers for small-bowel
neuroendocrine tumors (SBNET) to help guide clinical decisions. Background: MiRNAs are …

Background: Pancreatic neuroendocrine neoplasms (pNEN) are rare tumors with a poor
prognosis. Although increasing data have accumulated on the molecular pathology of …

The aim of this study was to define the miRNA profile of small intestinal neuroendocrine
tumors and to search for novel molecular subgroups and prognostic biomarkers. miRNA …