[HTML][HTML] Determination of the diagnostic accuracy of nanopore sequencing using bronchoalveolar lavage fluid samples from patients with sputum-scarce pulmonary …

L Zhou, X Zou, Q Hu, H Hua, Q Qi - Journal of Infection and Chemotherapy, 2024 - Elsevier
Purpose The early and efficient diagnosis of patients suspected of having pulmonary
tuberculosis (PTB) remains challenging. This study aimed to evaluate the accuracy of …

[HTML][HTML] Diagnostic accuracy of nanopore sequencing using respiratory specimens in the diagnosis of pulmonary tuberculosis

G Yu, Y Shen, F Zhong, L Zhou, G Chen, L Fang… - International Journal of …, 2022 - Elsevier
Objectives The aim of this study was to assess the role of nanopore sequencing using
respiratory specimens in the early diagnosis of pulmonary tuberculosis (PTB) and …

Nanopore sequencing for smear-negative pulmonary tuberculosis—a multicentre prospective study in China

X Yan, G Yang, Y Wang, Y Wang, J Cheng… - Annals of Clinical …, 2024 - Springer
Purpose In this prospective study, the diagnosis accuracy of nanopore sequencing-based
Mycobacterium tuberculosis (MTB) detection was determined through examining …

Diagnostic value of a nanopore sequencing assay of bronchoalveolar lavage fluid in pulmonary tuberculosis

Z Liu, Y Yang, Q Wang, L Wang, W Nie, N Chu - BMC pulmonary medicine, 2023 - Springer
Background To determine the diagnostic accuracy of a nanopore sequencing assay of PCR
products from a M. tuberculosis complex-specific region for testing of bronchoalveolar …

Evaluation of Nanopore Sequencing for Diagnosing Pulmonary Tuberculosis Using Negative Smear Clinical Specimens

G Yu, Y Shen, L Yao, X Xu - Infection and Drug Resistance, 2024 - Taylor & Francis
Purpose This study aimed to evaluate the efficacy of nanopore sequencing for diagnosing
pulmonary tuberculosis (PTB) using smear-negative clinical specimens. Methods We …

A preliminary evaluation of targeted nanopore sequencing technology for the detection of Mycobacterium tuberculosis in bronchoalveolar lavage fluid specimens

X Sun, J Song, X Leng, F Li, H Wang, J He… - Frontiers in Cellular …, 2023 - frontiersin.org
Objective To evaluate the efficacy of targeted nanopore sequencing technology for the
detection of Mycobacterium tuberculosis (M. tb.) in bronchoalveolar lavage fluid (BALF) …

Accuracy of nanopore sequencing as a diagnostic assay for pulmonary tuberculosis versus smear, culture and xpert MTB/RIF: a head-to-head comparison

J Yang, W Ye, C Zhang, W Lin, L Mei, S Liu… - Tropical medicine and …, 2023 - mdpi.com
Early diagnosis of pulmonary tuberculosis (PTB) is pivotal for achieving effective
tuberculosis (TB) control. This study aimed to assess the effectiveness of nanopore …

Targeted nanopore sequencing using clinical specimens for the rapid diagnosis of extrapulmonary tuberculosis

G Yu, L Fang, Y Shen, F Zhong, X Xu - BMC Infectious Diseases, 2024 - Springer
Background The clinical presentation of extrapulmonary tuberculosis (EPTB) is atypical and
it is easily confused with other diseases such as common infections, making prompt …

Diagnostic accuracy of nanopore sequencing for the rapid diagnosis of pulmonary tuberculosis: A protocol for a systematic review and meta-analysis

G Yu, X Xu, Y Shen, B Fang - Plos one, 2024 - journals.plos.org
Background Pulmonary tuberculosis (PTB) is the most common type of tuberculosis (TB).
Rapid diagnosis of PTB can help in TB control. Although the use of molecular tests (such as …

Exploring the accuracy of third-generation Nanopore Sequencing technology for detecting mycobacterium tuberculosis in patients with diabetes mellitus

C Song, C Zhao, Y Nong, Y Lin, A Huang, S Xi… - … and Infectious Disease, 2024 - Elsevier
Objective To explore the diagnostic value of third-generation nanopore sequencing
technology in patients with diabetes mellitus suspected of pulmonary tuberculosis. Methods …