The gut–brain axis and the microbiome: mechanisms and clinical implications

V Osadchiy, CR Martin, EA Mayer - Clinical Gastroenterology and …, 2019 - Elsevier
Background & Aims Based largely on results from preclinical studies, the concept of a brain
gut microbiome axis has been established, mediating bidirectional communication between …

Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis

MR Aburto, JF Cryan - Nature Reviews Gastroenterology & Hepatology, 2024 - nature.com
Crosstalk between gut and brain has long been appreciated in health and disease, and the
gut microbiota is a key player in communication between these two distant organs. Yet, the …

Gut microbiome–brain alliance: a landscape view into mental and gastrointestinal health and disorders

JM Sasso, RM Ammar, R Tenchov… - ACS Chemical …, 2023 - ACS Publications
Gut microbiota includes a vast collection of microorganisms residing within the
gastrointestinal tract. It is broadly recognized that the gut and brain are in constant …

Brain–gut–microbiota axis—mood, metabolism and behaviour

TG Dinan, JF Cryan - Nature reviews Gastroenterology & hepatology, 2017 - nature.com
In 2016, key studies have increased our understanding of the part played by the brain–gut–
microbiota axis in disorders as diverse as depression, obesity and autism spectrum disorder …

The microbiota-gut-brain axis: an emerging role for the epigenome

T Louwies, AC Johnson, A Orock… - Experimental …, 2020 - journals.sagepub.com
Through the gut-brain axis, the microorganisms that reside in the gut are able to exert an
important influence on the central nervous system. Preclinical and clinical evidence …

[HTML][HTML] The gut–brain axis

EA Mayer, K Nance, S Chen - Annual review of medicine, 2022 - annualreviews.org
Preclinical evidence has firmly established bidirectional interactions among the brain, the
gut, and the gut microbiome. Candidate signaling molecules and at least three …

Psychological comorbidity in gastrointestinal diseases: Update on the brain-gut-microbiome axis

H Person, L Keefer - Progress in Neuro-Psychopharmacology and …, 2021 - Elsevier
The high comorbidity of psychological disorders in both functional and organic
gastrointestinal diseases suggests the intimate and complex link between the brain and the …

[HTML][HTML] Crosstalk between the gut microbiota and the brain: an update on neuroimaging findings

P Liu, G Peng, N Zhang, B Wang, B Luo - Frontiers in neurology, 2019 - frontiersin.org
An increasing amount of evidence suggests that bidirectional communication between the
gut microbiome and the central nervous system (CNS), which is also known as the …

The interplay between the intestinal microbiota and the brain

SM Collins, M Surette, P Bercik - Nature Reviews Microbiology, 2012 - nature.com
The intestinal microbiota consists of a vast bacterial community that resides primarily in the
lower gut and lives in a symbiotic relationship with the host. A bidirectional neurohumoral …

[HTML][HTML] The brain-gut-microbiome axis

CR Martin, V Osadchiy, A Kalani, EA Mayer - Cellular and molecular …, 2018 - Elsevier
Preclinical and clinical studies have shown bidirectional interactions within the brain-gut-
microbiome axis. Gut microbes communicate to the central nervous system through at least …