Malaria is caused by protozoan parasites of the genus Plasmodium and involves infection of
multiple hosts and cell types during the course of an infection. To complete its complex life …

Malaria remains one of the most prevalent infectious diseases worldwide, affecting more
than half a billion people annually. Despite many years of research, the mechanisms …

A family of apicomplexa-specific proteins containing AP2 DNA-binding domains (ApiAP2s)
was identified in malaria parasites. This family includes sequence-specific transcription …

The molecular mechanisms underlying transcriptional regulation in apicomplexan parasites
remain poorly understood. Recently, the Apicomplexan AP2 (ApiAP2) family of DNA binding …

Putative transcription factors have only recently been identified in the Plasmodium spp., with
the major family of regulators comprising the Apicomplexan Apetala2 (AP2) proteins. To …

Apicomplexan parasites are protozoan organisms that are characterised by complex life
cycles and they include medically important species, such as the malaria parasite …

Variegated surface antigen expression is key to chronic infection and pathogenesis of the
human malaria parasite Plasmodium falciparum. This protozoan parasite expresses distinct …

Stage-specific transcription is a fundamental biological process in the life cycle of the
Plasmodium parasite. Proteins containing the AP2 DNA-binding domain are responsible for …

The comparative genomics of apicomplexans, such as the malarial parasite Plasmodium,
the cattle parasite Theileria and the emerging human parasite Cryptosporidium, have …

A major obstacle in analyzing gene function in apicomplexan parasites is the absence of a
practical regulatable expression system. Here, we identified functional transcriptional …