There is extensive evidence supporting the interference of inflammatory activation with
metabolism. Obesity, mainly visceral obesity, is associated with a low‐grade inflammatory …

There is still an unresolved paradox with respect to the immunomodulating role of estrogens.
On one side, we recognize inhibition of bone resorption and suppression of inflammation in …

The widely shared enthusiasm about the cardioprotective potential of estrogenic compounds
has come to an abrupt halt since randomized trials failed to show a cardiovascular risk …

The metabolic syndrome is a complex condition characterized by obesity, insulin resistance,
decreased high-density lipoproteins, and hypertension associated with high risk of …

Menopause-related decline in estrogen levels is accompanied by a change in adipose
tissue distribution from a gynoid to an android and an increased prevalence of obesity in …

Estrogen plays an important role in the regulation of cardiovascular physiology and the
immune system by inducing direct effects on multiple cell types including immune and …

The current knowledge of sex-dependent differences in adipose tissue biology remains in its
infancy and is motivated in part by the desire to understand why menopause is linked to an …

Obesity and its associated health disorders and costs are increasing. Men and post-
menopausal women have greater risk of developing complications of obesity than younger …

Recent publications describing the results of the Women's Health Initiative (WHI) and other
studies reporting the impact of hormone therapy on aging women have spurred …

Vascular inflammation underlies the pathogenesis of atherosclerosis. Atherosclerotic
changes in the vasculature lead to conditions such as coronary artery disease and stroke …