The EuroPhysiome, STEP and a roadmap for the virtual physiological human

JW Fenner, B Brook, G Clapworthy… - … of the Royal …, 2008 - royalsocietypublishing.org
Biomedical science and its allied disciplines are entering a new era in which computational
methods and technologies are poised to play a prevalent role in supporting collaborative …

A vision and strategy for the virtual physiological human in 2010 and beyond

P Hunter, PV Coveney, B De Bono… - … of the Royal …, 2010 - royalsocietypublishing.org
European funding under framework 7 (FP7) for the virtual physiological human (VPH)
project has been in place now for nearly 2 years. The VPH network of excellence (NoE) is …

The virtual physiological human—a european initiative for in silico human modelling—

M Viceconti, G Clapworthy, SVS Jan - The journal of physiological …, 2008 - jstage.jst.go.jp
Abstract The Virtual Physiological Human (VPH) is an initiative, strongly supported by the
European Commission (EC), that seeks to develop an integrated model of human …

Systems biology and the virtual physiological human

P Kohl, D Noble - Molecular Systems Biology, 2009 - embopress.org
The virtual physiological human (VPH) initiative is intended to support the development of
patient-specific computer models and their application in personalised and predictive …

The virtual physiological human: ten years after

M Viceconti, P Hunter - Annual review of biomedical …, 2016 - annualreviews.org
Biomedical research and clinical practice are struggling to cope with the growing complexity
that the progress of health care involves. The most challenging diseases, those with the …

The VPH-Physiome project: Standards and tools for multiscale modeling in clinical applications

PJ Hunter, M Viceconti - IEEE Reviews in Biomedical …, 2009 - ieeexplore.ieee.org
The revolution in molecular biology over the past 50 years has given us an extraordinarily
detailed parts list for life, but little understanding of how the parts integrate into the …

The virtual physiological human: the physiome project aims to develop reproducible, multiscale models for clinical practice

P Hunter - IEEE pulse, 2016 - ieeexplore.ieee.org
The Physiome Project was initiated by the International Union of Physiological Sciences
(IUPS; www. iups. org) in 1997 to bring multiscale engineering modeling approaches to the …

The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable

D Nickerson, K Atalag, B De Bono… - Interface …, 2016 - royalsocietypublishing.org
Reconstructing and understanding the Human Physiome virtually is a complex mathematical
problem, and a highly demanding computational challenge. Mathematical models spanning …

Modeling human physiology: The IUPS/EMBS physiome project

PJ Hunter - Proceedings of the IEEE, 2006 - ieeexplore.ieee.org
The Physiome Project is an international collaboration to provide a framework for
understanding human physiology, from proteins and cells to tissues and organs, with …

Knowledge environments representing molecular entities for the virtual physiological human

M Hofmann-Apitius, J Fluck… - … of the Royal …, 2008 - royalsocietypublishing.org
In essence, the virtual physiological human (VPH) is a multiscale representation of human
physiology spanning from the molecular level via cellular processes and multicellular …