Obesity leads to chronic, systemic inflammation and can lead to insulin resistance (IR), β-cell
dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state …

There are currently over 1.9 billion people who are obese or overweight, leading to a rise in
related health complications, including insulin resistance, type 2 diabetes, cardiovascular …

Obesity is becoming an epidemic in the United States and worldwide and increases risk for
many diseases, particularly insulin resistance, type 2 diabetes mellitus, and cardiovascular …

At least 2.8 million people die each year as a result of being overweight or obese, and the
biggest burden being obesity-related diseases. Overweight and obesity account for a major …

The worldwide obesity epidemic has emerged as a major cause of insulin resistance and
Type 2 diabetes. Chronic tissue inflammation is a well-recognized feature of obesity, and the …

The modern rise in obesity and its strong association with insulin resistance and type 2
diabetes have elicited interest in the underlying mechanisms of these pathologies. The …

Obesity and associated chronic inflammation initiate a state of insulin resistance (IR). The
secretion of chemoattractants such as MCP-1 and MIF and of cytokines IL-6, TNF-α, and IL …

Over the last decade, an abundance of evidence has emerged demonstrating a close link
between metabolism and immunity. It is now clear that obesity is associated with a state of …

Type 2 diabetes is now a worldwide epidemic, strongly correlated with an elevated
incidence of obesity. Obesity-associated adipose tissue inflammation is a major cause of the …

It is recognized that a chronic low-grade inflammation and an activation of the immune
system are involved in the pathogenesis of obesity-related insulin resistance and type 2 …