Advances in local drug delivery technologies for improved rheumatoid arthritis therapy

X An, J Yang, X Cui, J Zhao, C Jiang, M Tang… - Advanced Drug Delivery …, 2024 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by
an inflammatory microenvironment and cartilage erosion within the joint cavity. Currently …

Pathophysiology to advanced intra-articular drug delivery strategies: unravelling rheumatoid arthritis

H Singh, A Dan, MK Kumawat, V Pawar, DS Chauhan… - Biomaterials, 2023 - Elsevier
Rheumatoid arthritis (RA) is one of the most prevalent life-long autoimmune diseases with
an unknown genesis. It primarily causes chronic inflammation, pain, and synovial joint …

Drug Delivery System Approaches for Rheumatoid Arthritis Treatment: A Review

A Garhwal, P Kendya, S Soni, S Kori… - Mini Reviews in …, 2024 - ingentaconnect.com
Rheumatoid arthritis (RA) is a chronic autoimmune disease that has traditionally been
treated using a variety of pharmacological compounds. However, the effectiveness of these …

Recent advances in nano-targeting drug delivery systems for rheumatoid arthritis treatment

H Li, R Gou, J Liao, Y Wang, R Qu, Q Tang… - Acta Materia …, 2023 - scienceopen.com
Rheumatoid arthritis is a systemic inflammatory disease that can lead to articular cartilage
destruction and periarticular bone erosion, thus ultimately compromising joint integrity and …

Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis

MC Bruno, MC Cristiano, C Celia, N d'Avanzo… - ACS …, 2022 - ACS Publications
Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …

Targeted treatment for osteoarthritis: drugs and delivery system

L Mao, W Wu, M Wang, J Guo, H Li, S Zhang, J Xu… - Drug …, 2021 - Taylor & Francis
The management of osteoarthritis (OA) is a clinical challenge due to the particular avascular,
dense, and occluded tissue structure. Despite numerous clinical reports and animal studies …

Recent Advances in Clinical Translation of Intra‐Articular Osteoarthritis Drug Delivery Systems

CR DeJulius, S Gulati, KA Hasty… - Advanced …, 2021 - Wiley Online Library
Osteoarthritis (OA) is a degenerative disease of the joints and a leading cause of physical
disability in adults. Intra‐articular (IA) therapy is a popular treatment strategy for localized …

Targeted drug-delivery systems in the treatment of rheumatoid arthritis: recent advancement and clinical status

S Gorantla, G Singhvi, VK Rapalli, T Waghule… - Therapeutic …, 2020 - Taylor & Francis
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that is characterized by
synovial inflammation, cellular infiltration in joints which leads to progressive joint …

Emerging advances in nanomedicine as a nanoscale pharmacotherapy in rheumatoid arthritis: state of the art

M Rahman, G Sharma, K Thakur… - Current topics in …, 2017 - ingentaconnect.com
There are several significant setbacks including limited bioavailability, high clearance, and
further current therapies require higher and frequent dosing to gain desired therapeutic …

A comprehensive review of advanced drug delivery systems for the treatment of rheumatoid arthritis

Q Shen, Y Du - International Journal of Pharmaceutics, 2023 - Elsevier
Rheumatoid arthritis (RA), a chronic autoimmune disease, is characterized by articular pain
and swelling, synovial hyperplasia, and cartilage and bone destruction. Conventional …