Immunomodulatory therapy has become a promising method for the clinical treatment of
many diseases. Recently, pilot studies revealed that immunomodulatory therapy exhibited …

Antisense oligonucleotides (ASOs) are promising tools for gene silencing and have been
exploited as therapeutics for human disease. However, delivery of therapeutic ASOs to …

Unresolved inflammation is a hallmark of many deadly diseases including atherosclerosis, a
silent pathological condition behind majority of cardiovascular diseases. Yet, anti …

Nanoparticulate delivery platforms have shown promising advantages for vaccines in many
aspects. However, their application was limited so far by lengthy synthetic protocols, the …

Macrophages play essential roles in the progression of rheumatoid arthritis (RA), which are
polarized into the pro‐inflammatory M1 phenotype with significant oxidative stress and …

Immunogenic cell death (ICD) is a promising strategy in cancer immunotherapy to induce
high immunogenicity and activate the immune system. However, its efficacy is counteracted …

Utilizing nanoparticles to deliver subunit vaccines can be viewed as a promising strategy for
enhancing the immune response, especially with regard to cellular immunity to fight against …

Methotrexate (MTX) has been used as an anchor drug for the treatment of rheumatoid
arthritis (RA), while the patients with chronic MTX administration suffer from severe side …

Atherosclerosis remains the leading cause of a broad spectrum of deadliest cardiovascular
diseases. MicroRNA‐33 is a new therapeutic target for atherosclerosis due to its diverse …

In the past 15 years, enormous progress has been made in cancer nanotechnology, and a
several nanoparticles have entered clinical testing for cancer treatment. Among these …