COVID-19 pneumonia causes acute lung injury and acute respiratory distress syndrome
(ALI/ARDS) characterized by early pulmonary endothelial and epithelial injuries with altered …

Abstract Models of animals that are susceptible to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection can usefully evaluate the efficacy of vaccines and …

COVID-19 is characterized by an excessive inflammatory response and macrophage
hyperactivation, leading, in severe cases, to alveolar epithelial injury and acute respiratory …

The coronavirus disease 2019 (COVID-19) pandemic continues to represent a challenge for
public health globally since transmission of different variants of the virus does not seem to …

Mice are normally unaffected by SARS coronavirus 2 (SARS-CoV-2) infection since the virus
does not bind effectively to the murine version of the angiotensin-converting enzyme 2 …

The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2
(SARS-CoV-2) is the defining global health emergency of this century. GC-376 is a Mpro …

ABSTRACT Coronavirus disease 2019 (COVID-19) is a recent global pandemic. It is a
deadly human viral disease, caused by the severe acute respiratory syndrome coronavirus 2 …

Since the outbreak of COVID-19 at the end of 2019, its causative agent SARS-CoV-2 has
been spreading around the world for one and half a year. During the long global circulation …

Severe acute respiratory syndrome coronavirus 2, responsible for the severe acute
respiratory syndrome known as COVID-19, has rapidly spread in almost every country and …

The Coronavirus envelope (E) protein is a small structural protein with ion channel activity
that plays an important role in virus assembly, budding, immunopathogenesis and disease …