[HTML][HTML] The BNT162b2 vaccine induces humoral and cellular immune memory to SARS-CoV-2 Wuhan strain and the Omicron variant in children 5 to 11 years of age

BL Cinicola, E Piano Mortari, AM Zicari… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 mRNA vaccines prevent severe COVID-19 by generating immune memory,
comprising specific antibodies and memory B and T cells. Although children are at low risk …

[HTML][HTML] BNT162b2 booster vaccination elicits cross-reactive immunity against SARS-CoV-2 variants B. 1.1. 529 and B. 1.617. 2 in convalescents of all ages

B Jahrsdörfer, M Proffen, J Scholz, J Hägele… - Frontiers in …, 2022 - frontiersin.org
In this prospective observational cohort study we analyzed cellular and serological immune
response parameters against SARS-CoV-2 and current variants of concern (VOC) in 147 …

[HTML][HTML] Stronger and durable SARS-CoV-2 immune response to mRNA vaccines in 5–11 years old children with prior COVID-19

C Di Chiara, A Cantarutti, MR Petrara, F Bonfante… - Vaccine, 2024 - Elsevier
Background and objectives mRNA vaccines elicit a durable humoral response to SARS-CoV-
2 in adults, whereas evidence in children is scarce. This study aimed to assess the early and …

[HTML][HTML] BNT162b2 booster after heterologous prime-boost vaccination induces potent neutralizing antibodies and T cell reactivity against SARS-CoV-2 Omicron BA. 1 …

A Seidel, M Zanoni, R Groß, D Krnavek… - Frontiers in …, 2022 - frontiersin.org
In light of the decreasing immune protection against symptomatic SARS-CoV-2 infection
after initial vaccinations and the now dominant immune-evasive Omicron variants,'booster' …

[HTML][HTML] Humoral profiles of toddlers and young children following SARS-CoV-2 mRNA vaccination

N Nziza, Y Deng, L Wood, N Dhanoa… - Nature …, 2024 - nature.com
Although young children generally experience mild symptoms following infection with SARS-
CoV-2, severe acute and long-term complications can occur. SARS-CoV-2 mRNA vaccines …

[HTML][HTML] SARS-CoV-2 infected children form early immune memory responses dominated by nucleocapsid-specific CD8+ T cells and antibodies

K Lima, JC Fontoura, PO de Souza, T Fazolo… - Frontiers in …, 2022 - frontiersin.org
This is the third year of the SARS-CoV-2 pandemic, and yet most children remain
unvaccinated. COVID-19 in children manifests as mostly mild or asymptomatic, however …

[HTML][HTML] BNT162b2 mRNA vaccination leads to long-term protection from COVID-19 disease

C Rossi, P Lanuti, I Cicalini, D De Bellis… - Vaccines, 2021 - mdpi.com
The efficacy of SARS-CoV-2 mRNA-based vaccines in preventing COVID-19 disease has
been extensively demonstrated; however, it is of uttermost importance to acquire knowledge …

Memory b cells and memory T cells induced by SARS-CoV-2 booster vaccination or infection show different dynamics and responsiveness to the omicron variant

S Mise-Omata, M Ikeda, M Takeshita… - The Journal of …, 2022 - journals.aai.org
Although the immunological memory produced by BNT162b2 vaccination against severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been well studied and …

BNT162b2 vaccination induces durable SARS-CoV-2–specific T cells with a stem cell memory phenotype

G Guerrera, M Picozza, S D'Orso, R Placido… - Science …, 2021 - science.org
Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
effective in preventing hospitalization from severe COVID-19. However, multiple reports of …

[HTML][HTML] Long-Term Effectiveness of BNT162b2 Pfizer-BioNTech mRNA-Based Vaccine on B Cell Compartment: Efficient Recall of SARS-CoV-2-Specific Memory B …

R Busà, M Miele, MC Sorrentino, G Amico… - International Journal of …, 2022 - mdpi.com
At present, there is a lack of clinical evidence about the impact and long-term durability of
the immune response induced by the third dose of mRNA vaccines. In this study, we …