[HTML][HTML] Improved survival with ursodeoxycholic acid prophylaxis in allogeneic stem cell transplantation: long-term follow-up of a randomized study

T Ruutu, E Juvonen, M Remberger, K Remes… - Biology of Blood and …, 2014 - Elsevier
We report the long-term results of a prospective randomized study on the use of
ursodeoxycholic acid (UDCA) for prevention of hepatic complications after allogeneic stem …

Ursodeoxycholic acid for the prevention of hepatic complications in allogeneic stem cell transplantation

T Ruutu, B Eriksson, K Remes… - Blood, The Journal …, 2002 - ashpublications.org
The role of ursodeoxycholic acid (UDCA) in the prevention of hepatic complications after
allogeneic stem cell transplantation was studied in a prospective randomized open-label …

[HTML][HTML] Systematic review of controlled clinical trials on the use of ursodeoxycholic acid for the prevention of hepatic veno-occlusive disease in hematopoietic stem …

J Tay, A Tinmouth, D Fergusson, L Huebsch… - Biology of Blood and …, 2007 - Elsevier
Hepatic veno-occlusive disease (HVOD) is a serious life-threatening complication of
hematopoietic stem cell transplantation (HSCT). Currently, there is no optimal therapeutic …

[PDF][PDF] A randomized clinical trial of ursodeoxycholic acid as adjuvant treatment to prevent liver transplant rejection

D Barnes, D Talenti, G Cammell, M Goormastic… - …, 1997 - Wiley Online Library
Acute rejection following orthotopic liver transplantation is a common problem despite
current immunosuppressive regimens. Ursodeoxycholic acid (UDCA) has been shown in …

THE NORDIC MULTICENTER DOUBLE-BLIND RANDOMIZED CONTROLLED TRIAL OF PROPHYLACTIC URSODEOXYCHOLIC ACID IN LIVER TRANSPLANT …

S Keiding, K Höckerstedt, K Bjøro, S Bondesen… - …, 1997 - journals.lww.com
Background. Prophylactic treatment with ursodeoxycholic acid (UDCA) has been reported to
reduce the incidence of acute rejection after liver transplantation compared with historical …

A prospective, randomized, double-blind trial evaluating the efficacy of ursodeoxycholic acid in prevention of liver transplant rejection

JF Fleckenstein, M Paredes, PJ Thuluvath - Liver Transplantation, 1998 - journals.lww.com
Acute cellular rejection (ACR) after orthotopic liver transplantation occurs in 50% to 80% of
patients despite the recent advances in immunosuppressive therapy. Adjuvant use of …

The Japanese multicenter open randomized trial of ursodeoxycholic acid prophylaxis for hepatic veno‐occlusive disease after stem cell transplantation

K Ohashi, J Tanabe, R Watanabe… - American journal of …, 2000 - Wiley Online Library
Hepatic veno‐occlusive disease (VOD) is a common transplant‐related complication of stem
cell transplantation. There is no safe and proven therapy for established VOD, and attempts …

Ursodeoxycholic acid treatment in isolated chronic graft‐vs.‐host disease of the liver

M Arat, R Idilman, EA Soydan, I Soykan… - Clinical …, 2005 - Wiley Online Library
Objectives: Data regarding the long‐term treatment of ursodeoxycholic acid (UDCA) in
individuals of chronic graft‐vs.‐host disease (cGVHD) of the liver are limited. The aims of this …

Pilot trial of prophylactic ursodiol to decrease the incidence of veno-occlusive disease of the liver in allogeneic bone marrow transplant patients.

JH Essell, JM Thompson, GS Harman… - Bone marrow …, 1992 - europepmc.org
Ursodiol is a hydrophilic, non-hepatotoxic bile salt indicated for the medical treatment of
cholesterol gallstones. This pilot study explored the use of prophylactic ursodiol in an …

Failure of ursodeoxycholic acid to prevent acute cellular rejection after liver transplantation

GP Pageaux, P Blanc, PF Perrigault, F Navarro… - Journal of …, 1995 - Elsevier
Background/Aims: Acute rejection is still a major problem after liver transplantation.
Ursodeoxycholic acid has beneficial effects in cholestasis by reducing the expression of …