[HTML][HTML] Wnt/β-Catenin signaling pathway in hepatocellular carcinoma: pathogenic role and therapeutic target

Z Zhao, T Cui, F Wei, Z Zhou, Y Sun, C Gao… - Frontiers in …, 2024 - frontiersin.org
Hepatocellular carcinoma (HCC) is the most common primary malignant liver tumor and one
of the leading causes of cancer-related deaths worldwide. The Wnt/β-Catenin signaling …

[HTML][HTML] Wnt-/-β-catenin pathway signaling in human hepatocellular carcinoma

J Waisberg, GT Saba - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
The molecular basis of the carcinogenesis of hepatocellular carcinoma (HCC) has not been
adequately clarified, which negatively impacts the development of targeted therapy …

Atypical regulators of Wnt/β-catenin signaling as potential therapeutic targets in hepatocellular carcinoma

J Chen, M Rajasekaran, KM Hui - Experimental biology and …, 2017 - journals.sagepub.com
Hepatocellular carcinoma is one of the most common causes of cancer-related death
worldwide. Hepatocellular carcinoma development depends on the inhibition and activation …

Wnt/β-catenin signaling as a driver of hepatocellular carcinoma progression: an emphasis on molecular pathways

M Deldar Abad Paskeh, S Mirzaei… - Journal of …, 2021 - Taylor & Francis
Liver cancers cause a high rate of death worldwide and hepatocellular carcinoma (HCC) is
considered as the most common primary liver cancer. HCC remains a challenging disease …

Wnt/β-catenin signaling pathway and its role in hepatocellular carcinoma

X Zhang, L Yu, Y Lu - Frontiers of Medicine in China, 2008 - Springer
Wnt/β-catenin signaling pathway has been identified as a key cellular pathway in
embryogenesis and disease, including cancers. In recent years, more and more interacting …

The Wnt/β-catenin pathway as a therapeutic target in human hepatocellular carcinoma

R Dahmani, PA Just, C Perret - Clinics and research in hepatology and …, 2011 - Elsevier
Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death
worldwide. However, targeted therapies are still at their beginning for the treatment of this …

Dysregulation of Wnt/β‐catenin signaling by protein kinases in hepatocellular carcinoma and its therapeutic application

Q Li, M Sun, M Wang, M Feng, F Yang, L Li… - Cancer …, 2021 - Wiley Online Library
Wnt/β‐catenin signaling is indispensable for many biological processes, including
embryonic development, cell cycle, inflammation, and carcinogenesis. Aberrant activation of …

Role of Wnt/β-catenin signaling pathway in promoting tumorigenesis of hepatocellular carcinoma

L Xie, H Jiang, F Wu - Nan Fang yi ke da xue xue bao= Journal of …, 2014 - europepmc.org
Wnt/β-catenin signaling pathway has a close relationship with cancer and is abnormally
activated in many human cancers. Hepatocellular carcinoma (HCC) is the third most …

WNT/β-catenin pathway activation in hepatocellular carcinoma: a clinical perspective

L Ma, W Wei, MS Chua, S So - Gastrointestinal Cancer: Targets …, 2014 - Taylor & Francis
Hepatocellular carcinoma (HCC) is a significant global health concern which requires
multidisciplinary approaches in its management. However, apart from surgical resection of …

Role of Wnt/β-catenin signaling in hepatocellular carcinoma, pathogenesis, and clinical significance

AM Khalaf, D Fuentes, AI Morshid… - Journal of …, 2018 - Taylor & Francis
Hepatocellular carcinoma (HCC) is one of the most common primary hepatic malignancies
and one of the fastest-growing causes of cancer-related mortality in the United States. The …