Model of dynamic speckle evolution for evaluating laser speckle contrast measurements of tissue dynamics

S Zilpelwar, EJ Sie, D Postnov, AI Chen… - Biomedical Optics …, 2022 - opg.optica.org
We introduce a dynamic speckle model (DSM) to simulate the temporal evolution of fully
developed speckle patterns arising from the interference of scattered light reemitted from …

Measurements of slow tissue dynamics with short-separation speckle contrast optical spectroscopy

B Liu, S Shah, G Küreli, A Devor, DA Boas… - Biomedical Optics …, 2023 - opg.optica.org
Laser speckle contrast imaging (LSCI) measures 2D maps of cerebral blood flow (CBF) in
small animal brains such as mice. The contrast measured in LSCI also includes the static …

Dynamic light scattering and laser speckle contrast imaging of the brain: theory of the spatial and temporal statistics of speckle pattern evolution

B Liu, D Postnov, DA Boas, X Cheng - Biomedical Optics Express, 2024 - opg.optica.org
Dynamic light scattering (DLS) and laser speckle contrast imaging (LSCI) are closely related
techniques that exploit the statistics of speckle patterns, which can be utilized to measure …

Dynamic laser speckle imaging of cerebral blood flow

P Zakharov, AC Völker, MT Wyss, F Haiss… - Optics express, 2009 - opg.optica.org
Laser speckle imaging (LSI) based on the speckle contrast analysis is a simple and robust
technique for imaging of heterogeneous dynamics. LSI finds frequent application for …

Effects of speckle/pixel size ratio on temporal and spatial speckle-contrast analysis of dynamic scattering systems: Implications for measurements of blood-flow …

JC Ramirez-San-Juan, E Mendez-Aguilar… - Biomedical optics …, 2013 - opg.optica.org
Laser Speckle Contrast Imaging (LSCI) is an optical technique used to generate blood flow
maps with high spatial and temporal resolution. It is well known that in LSCI, the speckle size …

Multi-mode fiber-based speckle contrast optical spectroscopy: analysis of speckle statistics

CHP Lin, I Orukari, C Tracy, LK Frisk, M Verma… - Optics Letters, 2023 - opg.optica.org
Speckle contrast optical spectroscopy/tomography (SCOS/T) provides a real-time, non-
invasive, and cost-efficient optical imaging approach to mapping of cerebral blood flow. By …

Robust quantitative single-exposure laser speckle imaging with true flow speckle contrast in the temporal and spatial domains

C Wang, Z Cao, X Jin, W Lin, Y Zheng… - Biomedical Optics …, 2019 - opg.optica.org
A systematic and robust laser speckle contrast imaging (LSCI) method and procedure is
presented covering the LSCI system calibration, static scattering removal, and measurement …

Sensitivity of laser speckle contrast imaging to flow perturbations in the cortex

MA Davis, L Gagnon, DA Boas… - Biomedical optics express, 2016 - opg.optica.org
Laser speckle contrast imaging has become a ubiquitous tool for imaging blood flow in a
variety of tissues. However, due to its widefield imaging nature, the measured speckle …

Correction for spatial averaging in laser speckle contrast analysis

O Thompson, M Andrews, E Hirst - Biomedical optics express, 2011 - opg.optica.org
Practical laser speckle contrast analysis systems face a problem of spatial averaging of
speckles, due to the pixel size in the cameras used. Existing practice is to use a system …

Handheld motion stabilized laser speckle imaging

B Lertsakdadet, C Dunn, A Bahani… - Biomedical optics …, 2019 - opg.optica.org
Laser speckle imaging (LSI) is a wide-field, noninvasive optical technique that allows
researchers and clinicians to quantify blood flow in a variety of applications. However …