Major depressive disorder (MDD) is a common, debilitating, phenotypically heterogeneous disorder with heritability ranges from 30% to 50%. Compared to other psychiatric disorders …
DF Levinson, S Mostafavi… - Biological …, 2014 - biologicalpsychiatryjournal.com
Over the past 5 years, the genome-wide association study (GWAS) method has produced significant findings that are providing insights into the biological pathways involved in …
FJ Bosker, CA Hartman, IM Nolte, BP Prins… - Molecular …, 2011 - nature.com
Abstract Data from the Genetic Association Information Network (GAIN) genome-wide association study (GWAS) in major depressive disorder (MDD) were used to explore …
Major Depressive Disorder Working Group of … - Molecular …, 2013 - ncbi.nlm.nih.gov
Prior genome-wide association studies (GWAS) of major depressive disorder (MDD) have met with limited success. We sought to increase statistical power to detect disease loci by …
There have been several recent studies addressing the genetic architecture of depression. This review serves to take stock of what is known now about the genetics of depression, how …
The recent successful genome-wide association studies (GWASs) for depression have yielded more than 80 replicated loci and brought back the excitement that had evaporated …
Major depressive disorder (MDD) is a common mental disorder generally characterized by symptoms associated with mood, pleasure and effectiveness in daily life activities. MDD is …
With progress in genome-wide association studies of depression, from identifying zero hits in~ 16 000 individuals in 2013 to 223 hits in more than a million individuals in 2020 …
FW Lohoff - Current psychiatry reports, 2010 - Springer
Major depressive disorder (MDD) is a common psychiatric illness with high levels of morbidity and mortality. Despite intensive research during the past several decades, the …