There is cumulative evidence that young people in an “at-risk mental state”(ARMS) for
psychosis show structural brain abnormalities in frontolimbic areas, comparable to, but less …

Background Individuals at clinical high risk (CHR) who progress to fully psychotic symptoms
have been observed to show a steeper rate of cortical gray matter reduction compared with …

Schizophrenia has been associated with reduced volumes of subcortical structures on
magnetic resonance imaging (MRI), but the relation of these reductions to familial risk for the …

Importance Structural brain abnormalities are prominent in psychotic disorders, including
schizophrenia. However, it is unclear when aberrations emerge in the disease process and …

Background Studies to date examining cortical thickness and surface area in young
individuals At Risk Mental State (ARMS) of developing psychosis have revealed inconsistent …

Background The evaluation of child and adolescent offspring of patients with schizophrenia
(SzO) or bipolar disorder (BpO) may help understand changes taking place in the brain in …

de Castro‐Manglano P, Mechelli A, Soutullo C, Landecho I, Gimenez‐Amaya JM, Ortuño F,
McGuire P. Structural brain abnormalities in first‐episode psychosis: differences between …

BACKGROUND:: Regional prefrontal cortex gray matter reductions have been identified in
schizophrenia, likely reflecting a combination of genetic vulnerability and disease effects …

OBJECTIVE: The objective of the present study is to replicate findings in first-episode
psychosis reporting a smaller volume in brain structures in a population with adolescent …

Background: Several cross-sectional studies report brain structure differences between
healthy volunteers and subjects at genetic or clinical high risk of developing schizophrenia …