Carnosine was first discovered in skeletal muscle, where its concentration is higher than in
any other tissue. This, along with an understanding of its role as an intracellular pH buffer …

Carnosine was originally discovered in skeletal muscle, where it exists in larger amounts
than in other tissues. The majority of research into the physiological roles of carnosine have …

Carnosine (β-alanyl-L-histidine) plays an important role in exercise performance and
skeletalmuscle homeostasis. Dietary supplementation with the rate-limiting precursor β …

Carnosine is a dipeptide with a high concentration in mammalian skeletal muscle. It is
synthesized by carnosine synthase from the amino acids L-histidine and β-alanine, of which …

On the basis of the millimolar presence of carnosine in mammalian muscles, it must play a
critical role in skeletal muscle physiology. The recent number of studies shows that this is …

β-alanine is an amino acid that, when combined with histidine, forms the dipeptide
carnosine within skeletal muscle. Carnosine and β-alanine each have multiple purposes …

Carnosine is an abundant histidine-containing dipeptide in human skeletal muscle and
formed by beta-alanine and L-histidine. It performs various physiological roles during …

Interest into the effects of carnosine on cellular metabolism is rapidly expanding. The first
study to demonstrate in humans that chronic β-alanine (BA) supplementation (~ 3–6 g …

Abstract β-Alanine is a nonproteogenic amino acid that combines with histidine to form a
dipeptide molecule known as carnosine. Carnosine is an H+ buffer that is especially useful …

High-intensity exercise leads to reductions in muscle substrates (ATP, PCr, and glycogen)
and a subsequent accumulation of metabolites (ADP, Pi, H+, and Mg 2+) with a possible …