Mucosal healing in ulcerative colitis: a comprehensive review

P Boal Carvalho, J Cotter - Drugs, 2017 - Springer
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by periods of
remission and periods of relapse. Patients often present with symptoms such as rectal …

Importance of mucosal healing in ulcerative colitis

GR Lichtenstein, P Rutgeerts - Inflammatory bowel diseases, 2010 - academic.oup.com
Abstract Treatment of patients with ulcerative colitis (UC) has traditionally focused on
improving symptoms, with the main objective of inducing and maintaining symptomatic …

Mucosal healing is associated with improved long-term outcomes of patients with ulcerative colitis: a systematic review and meta-analysis

SC Shah, JF Colombel, BE Sands, N Narula - Clinical gastroenterology and …, 2016 - Elsevier
Background & Aims The paradigm for treatment for ulcerative colitis (UC) is shifting from
resolving symptoms toward objective measures such as mucosal healing (MH). However, it …

[HTML][HTML] Novel oral-targeted therapies for mucosal healing in ulcerative colitis

E Antonelli, V Villanacci, G Bassotti - World journal of …, 2018 - ncbi.nlm.nih.gov
Ulcerative colitis (UC), a chronic, relapsing, remitting disease of the colon and rectum, is
characterized by inflammatory ulceration of the mucosa. Current UC therapy relies on …

Histological healing: should it be considered as a new outcome for ulcerative colitis?

A Dal Buono, G Roda, M Argollo… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction: Currently, mucosal healing is considered as a composite treatment end-point in
inflammatory bowel disease (IBD) since it has been demonstrated to improve disease …

Feasibility of endoscopic assessment and treating to target to achieve mucosal healing in ulcerative colitis

G Bouguen, BG Levesque, S Pola… - Inflammatory bowel …, 2014 - academic.oup.com
Background Mucosal healing (MH) as a treatment target for ulcerative colitis is of growing
interest because it is associated with improved clinical outcomes. However, the feasibility …

Is histological healing a feasible endpoint in ulcerative colitis?

T Rath, R Atreya, MF Neurath - Expert Review of Gastroenterology …, 2021 - Taylor & Francis
Introduction Currently, treatment goals in ulcerative colitis aim to achieve clinical remission
and endoscopic mucosal healing. Emerging evidence suggests that histologic assessment …

Mucosal healing in inflammatory bowel disease: where do we stand?

C Ha, A Kornbluth - Current gastroenterology reports, 2010 - Springer
The definition of remission in Crohn's disease and ulcerative colitis has evolved to include
mucosal healing as a measure of treatment efficacy. Randomized, controlled trials have …

[HTML][HTML] Mucosal healing in inflammatory bowel disease: treatment efficacy and predictive factors

C Papi, F Fascì-Spurio, F Rogai, A Settesoldi… - Digestive and Liver …, 2013 - Elsevier
In recent years mucosal healing has emerged as an important therapeutic goal for patients
with inflammatory bowel disease. Growing evidence suggests that achieving mucosal …

Results from the 2nd Scientific Workshop of the ECCO (I): Impact of mucosal healing on the course of inflammatory bowel disease

L Peyrin-Biroulet, M Ferrante, F Magro… - Journal of Crohn's …, 2011 - academic.oup.com
Over the past years, mucosal healing has emerged as a major therapeutic goal in clinical
trials in inflammatory bowel diseases. Accumulating evidence indicates that mucosal …