Critical evaluation of asthma biomarkers in clinical practice

G Guida, D Bagnasco, V Carriero, F Bertolini… - Frontiers in …, 2022 - frontiersin.org
The advent of personalized medicine has revolutionized the whole approach to the
management of asthma, representing the essential basis for future developments. The …

Biomarkers in asthma: state of the art

A Tiotiu - Asthma research and practice, 2018 - Springer
Asthma is a heterogenous disease characterized by multiple phenotypes driven by different
mechanisms. The implementation of precision medicine in the management of asthma …

Clinical utility of asthma biomarkers: from bench to bedside

SJH Vijverberg, B Hilvering… - … : Targets and Therapy, 2013 - Taylor & Francis
Asthma is a chronic disease characterized by airway inflammation, bronchial
hyperresponsiveness, and recurrent episodes of reversible airway obstruction. The disease …

Recent insights in the role of biomarkers in severe asthma management

E Fouka, K Domvri, F Gkakou, M Alevizaki… - Frontiers in …, 2022 - frontiersin.org
Contemporary asthma management requires a proactive and individualized approach,
combining precision diagnosis and personalized treatment. The introduction of biologic …

[HTML][HTML] Allergic and eosinophilic asthma in the era of biomarkers and biologics: similarities, differences and misconceptions

J Oppenheimer, FCL Hoyte, W Phipatanakul… - Annals of Allergy …, 2022 - Elsevier
Objective Severe asthma is associated with substantial personal and economic burden;
maintaining disease control is the key management goal. Increased understanding of …

Biomarkers in the assessment and management of airways diseases

DR Taylor, ID Pavord - Postgraduate medical journal, 2008 - academic.oup.com
A plethora of biomarkers are becoming available in the field of respiratory medicine, but their
application in clinical practice has been limited. This is changing. There is increasing scope …

Can biomarkers help us hit targets in difficult‐to‐treat asthma?

M Fricker, LG Heaney, JW Upham - Respirology, 2017 - Wiley Online Library
Biomarkers may be a key foundation for the precision medicine of the future. In this article,
we review current knowledge regarding biomarkers in difficult‐to‐treat asthma and their …

Asthma biomarkers: what constitutes a 'gold standard'?

JR Arron, K Izuhara - Thorax, 2015 - thorax.bmj.com
Many studies have assessed sputum eosinophil percentage as a phenotypic descriptor in
asthma patients. Adjusting inhaled corticosteroid (ICS) dose based on sputum eosinophilia …

Inflammatory biomarkers for asthma endotyping and consequent personalized therapy

G Ciprandi, MA Tosca, M Silvestri… - Expert Review of …, 2017 - Taylor & Francis
Introduction: We argue that asthma be considered a syndrome caused by multiple
inflammatory pathogenic processes. Bronchial hyperresponsiveness, reversible airflow …

Biomarkers and asthma management: analysis and potential applications

LB Richards, AH Neerincx… - Current opinion in …, 2018 - journals.lww.com
Individualisation of asthma treatment regimens on the basis of biomarkers is necessary to
improve asthma control. However, the suboptimal properties of currently available …