Glycosaminoglycans (GAGs) are important constituents of human glycome. They are negatively charged unbranched polysaccharides that are usually covalently attached to …
The growing recognition of the structural complexity and functional importance of glycoconjugates, including glycoproteins, glycolipids, and glycosaminoglycans, in biological …
ML Huang, K Godula - ACS chemical neuroscience, 2014 - ACS Publications
Glycans are important contributors to the development and function of the nervous system with enormous potential as therapeutic targets. However, a general lack of tools for tailoring …
W Jin, F Zhang, RJ Linhardt - The Role of Glycosylation in Health and …, 2021 - Springer
Glycosaminoglycans (GAGs) are linear polysaccharides that consist of alternating disaccharides sequences of uronic acids and/or galactose hexamino sugars most of which …
VP Bhavanandan, DC Gowda - Glycobiology of the Nervous System, 2014 - Springer
This chapter provides an overview of structures and functions of complex carbohydrates (commonly called glycans) that are covalently linked to proteins or lipids to form …
B Gesslbauer, AJ Kungl - Current opinion in molecular …, 2006 - researchgate.net
The science of decoding the information contained within complex glycan structures is commonly referred to as' glycomics'. Information flow is usually governed by the binding of …
Glycosaminoglycans (GAGs), linear macromolecular heteropolysaccharides consisting of disaccharide repeating units, are classified into several types. Hexuronic acid based GAGs …
ME Griffin, LC Hsieh-Wilson - Current opinion in chemical biology, 2013 - Elsevier
Highlights•Synthetic oligosaccharides link specific structures to biological functions.• Chemoenzymatic methods can produce therapeutically active oligosaccharides.•Biomimetic …
ZS Clauss, JR Kramer - Advanced Drug Delivery Reviews, 2021 - Elsevier
Carbohydrates play essential structural and biochemical roles in all living organisms. Glycopolymers are attractive as well-defined biomimetic analogs to study carbohydrate …