[HTML][HTML] Immune control of HIV
M Balasubramaniam, J Pandhare… - Journal of life sciences …, 2019 - ncbi.nlm.nih.gov
The human immunodeficiency virus (HIV) infection of the immune cells expressing the
cluster of differentiation 4 cell surface glycoprotein (CD4+ cells) causes progressive decline …
cluster of differentiation 4 cell surface glycoprotein (CD4+ cells) causes progressive decline …
Lessons to be learned from natural control of HIV–future directions, therapeutic, and preventive implications
D Shasha, BD Walker - Frontiers in immunology, 2013 - frontiersin.org
Accumulating data generated from persons who naturally control HIV without the need for
antiretroviral treatment has led to significant insights into the possible mechanisms of …
antiretroviral treatment has led to significant insights into the possible mechanisms of …
Unravelling the mechanisms of durable control of HIV-1
Untreated HIV-1 infection typically progresses to AIDS within 10 years, but less than 1% of
infected individuals remain healthy and have normal CD4+ T cell counts and undetectable …
infected individuals remain healthy and have normal CD4+ T cell counts and undetectable …
HIV controllers: a genetically determined or inducible phenotype?
A Sáez‐Cirión, G Pancino - Immunological reviews, 2013 - Wiley Online Library
Summary Less than 0.5% of human immunodeficiency virus‐1 (HIV‐1)‐infected patients
maintain viral load below the threshold of detection by conventional assays for many years …
maintain viral load below the threshold of detection by conventional assays for many years …
HIV controllers have low inflammation associated with a strong HIV-specific immune response in blood
H Hocini, H Bonnabau, C Lacabaratz… - Journal of …, 2019 - Am Soc Microbiol
ABSTRACT HIV controllers (HIC) maintain control of HIV replication without combined
antiretroviral treatment (cART). The mechanisms leading to virus control are not fully known …
antiretroviral treatment (cART). The mechanisms leading to virus control are not fully known …
HIV-specific CD8+ T cells and HIV eradication
After the success of combination antiretroviral therapy (cART) to treat HIV infection, the next
great frontier is to cure infected persons, a formidable challenge. HIV persists in a quiescent …
great frontier is to cure infected persons, a formidable challenge. HIV persists in a quiescent …
Targeted immune interventions for an HIV-1 cure
M Perreau, R Banga, G Pantaleo - Trends in molecular medicine, 2017 - cell.com
Combination antiretroviral therapy (cART) induces durable suppression of virus replication
but is unable to eradicate HIV. Invariably, virus rebound follows treatment interruption and …
but is unable to eradicate HIV. Invariably, virus rebound follows treatment interruption and …
Can HIV-1-specific ADCC assist the clearance of reactivated latently infected cells?
WS Lee, MS Parsons, SJ Kent, M Lichtfuss - Frontiers in immunology, 2015 - frontiersin.org
Combination antiretroviral therapy (cART) has transformed the outcome of human
immunodeficiency virus-1 (HIV-1) infection from a severe immunodeficiency syndrome to a …
immunodeficiency virus-1 (HIV-1) infection from a severe immunodeficiency syndrome to a …
HIV controllers: a multifactorial phenotype of spontaneous viral suppression
J Thèze, LA Chakrabarti, B Vingert, F Porichis… - Clinical …, 2011 - Elsevier
A small minority of HIV-infected individuals, known as HIV controllers, is able to exert long-
term control over HIV replication in the absence of treatment. Increasing evidence suggests …
term control over HIV replication in the absence of treatment. Increasing evidence suggests …
Human immunodeficiency virus type-1 elite controllers maintain low co-expression of inhibitory receptors on CD4+ T cells
Human immunodeficiency virus type-1 (HIV-1) elite controllers (ELCs) represent a unique
population that control viral replication in the absence of antiretroviral therapy (cART). It is …
population that control viral replication in the absence of antiretroviral therapy (cART). It is …