Use of tocilizumab in kidney transplant recipients with COVID‐19

MJ Pérez‐Sáez, M Blasco… - American Journal of …, 2020 - Wiley Online Library
Acute respiratory distress syndrome associated with coronavirus infection is related to a
cytokine storm with large interleukin‐6 (IL‐6) release. The IL‐6‐receptor blocker tocilizumab …

Tocilizumab for severe COVID‐19 in solid organ transplant recipients: a matched cohort study

MR Pereira, MM Aversa, MA Farr… - American Journal of …, 2020 - Wiley Online Library
The safety and efficacy of tocilizumab for the treatment of severe respiratory symptoms due
to COVID‐19 remain uncertain, in particular among solid organ transplant (SOT) recipients …

COVID-19 in kidney transplant recipients

I Gandolfini, M Delsante, E Fiaccadori… - American Journal of …, 2020 - amjtransplant.org
An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that began
in Wuhan, China, has spread rapidly and has already taken on pandemic proportions. 1 …

Interleukin-6 receptor blocking with intravenous tocilizumab in COVID-19 severe acute respiratory distress syndrome: A retrospective case-control survival analysis of …

LM Canziani, S Trovati, E Brunetta, A Testa… - Journal of …, 2020 - Elsevier
In cases of COVID-19 acute respiratory distress syndrome, an excessive host inflammatory
response has been reported, with elevated serum interleukin-6 levels. In this multicenter …

Impact of tocilizumab administration on mortality in severe COVID-19

A Tsai, O Diawara, RG Nahass, L Brunetti - Scientific reports, 2020 - nature.com
The novel coronavirus disease 2019 (COVID-19) worldwide pandemic has placed a
significant burden on hospitals and healthcare providers. The immune response to this …

Clinical course of COVID‐19 in a liver transplant recipient on hemodialysis and response to tocilizumab therapy: a case report

MB Hammami, B Garibaldi, P Shah… - American Journal of …, 2020 - Wiley Online Library
The novel coronavirus disease 2019 (COVID‐19) is a highly infectious and rapidly
spreading disease. There are limited published data on the epidemiology and outcomes of …

Effects of Tocilizumab in COVID-19 patients: a cohort study

CA Vu, KJ DeRonde, AD Vega, M Maxam, G Holt… - BMC infectious …, 2020 - Springer
Background Due to the lack of proven therapies, we evaluated the effects of early
administration of tocilizumab for COVID-19. By inhibition of the IL-6 receptor, tocilizumab …

Tocilizumab in hospitalized patients with COVID‐19: clinical outcomes, inflammatory marker kinetics, and safety

JA Hill, MP Menon, S Dhanireddy… - Journal of medical …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) due to infection with severe acute
respiratory syndrome coronavirus 2 causes substantial morbidity. Tocilizumab, an …

[HTML][HTML] A single center observational study of the clinical characteristics and short-term outcome of 20 kidney transplant patients admitted for SARS-CoV2 pneumonia

F Alberici, E Delbarba, C Manenti, L Econimo… - Kidney international, 2020 - Elsevier
The outcome of SARS-CoV2 infection in patients who have received a kidney allograft and
are being treated with immunosuppression is unclear. We describe 20 kidney transplant …

[HTML][HTML] Repurposed tocilizumab in patients with severe COVID-19

J Tian, M Zhang, M Jin, F Zhang, Q Chu… - The Journal of …, 2021 - journals.aai.org
The coronavirus disease 2019 (COVID-19) has caused a global pandemic, resulting in
considerable morbidity and mortality. Tocilizumab, an inhibitor of IL-6, has been widely …