Early versus delayed angiotensin-converting enzyme inhibition therapy in acute myocardial infarction: the healing and early afterload reducing therapy trial

MA Pfeffer, SC Greaves, JMO Arnold, RJ Glynn… - Circulation, 1997 - Am Heart Assoc
Background Although ACE inhibitor therapy has been shown to reduce mortality in patients
with acute myocardial infarction (MI), the optimal dose and the timing of its initiation have not …

Which patient benefits from early angiotensin-converting enzyme inhibition after myocardial infarction? Results of one-year serial echocardiographic follow-up from …

WH Van Gilst, JH Kingma, KH Peels… - Journal of the American …, 1996 - Elsevier
Objectives. In this study we sought to investigate the effect of intervention with captopril
within 6 h of the onset of myocardial infarction on left ventricular volume and clinical …

Effects of early and late administration of angiotensin-converting enzyme inhibitors on mortality after myocardial infarction

EJ Rodrigues, MJ Eisenberg, L Pilote - The American journal of medicine, 2003 - Elsevier
BACKGROUND: Clinical trials demonstrating that angiotensin-converting enzyme (ACE)
inhibitors reduce mortality when prescribed following myocardial infarction have focused on …

Clinical effects of early angiotensin-converting enzyme inhibitor treatment for acute myocardial infarction are similar in the presence and absence of aspirin: systematic …

R Latini, G Tognoni, AP Maggioni, MG Franzosi… - Journal of the American …, 2000 - jacc.org
OBJECTIVES We sought to determine whether the clinical effects of early angiotensin-
converting enzyme (ACE) inhibitor (ACEi) treatment for acute myocardial infarction (MI) are …

Effect of angiotensin-converting enzyme inhibitors on ventricular remodeling and survival following myocardial infarction

C Beckwith, MA Munger - Annals of Pharmacotherapy, 1993 - journals.sagepub.com
OBJECTIVE: To discuss the effects of angiotensin-converting enzyme (ACE) inhibitors on
ventricular remodeling and survival after acute myocardial infarction (AMI). An overview is …

ACE inhibitors in acute myocardial infarction: patient selection and timing

MA Pfeffer - Circulation, 1998 - Am Heart Assoc
Angiotensin-converting enzyme inhibitors have earned their place along with aspirin,-
blockers, and thrombolytic agents as medical therapies proven to reduce mortality rates in …

“Cardioprotection” by ACE-inhibitors in acute myocardial ischemia and infarction?

K Przyklenk, RA Kloner - Angiotensin and the Heart, 1993 - Springer
Coronary artery occlusion results in the acute activation of the renin-angiotensin system and
production of angiotensin II, a potent vasoconstrictor and positive inotropic agent. This has …

Enhancing cardiac protection after myocardial infarction: rationale for newer clinical trials of angiotensin receptor blockers

MA Pfeffer - American heart journal, 2000 - Elsevier
Treatment of acute myocardial infarction (MI) has been advanced considerably in the past
20 years with the advent of acute reperfusion strategies such as thrombolytic therapy or …

Causes of death in patients with acute myocardial infarction treated with angiotensin-converting enzyme inhibitors: Findings from the Gruppo Italiano per lo Studio …

G Pedrazzini, E Santoro, R Latini, L Fromm… - American heart …, 2008 - Elsevier
BACKGROUND: The causes of death occurring in clinical trials of myocardial infarction (MI)
are scarcely reported in the literature. The present analysis is aimed to describe the …

Effects of losartan and captopril on left ventricular systolic and diastolic function after acute myocardial infarction: results of the Optimal Trial in Myocardial Infarction …

JE Møller, U Dahlström, O Gøtzsche, A Lahiri… - American Heart …, 2004 - Elsevier
BACKGROUND: Angiotensin-converting enzyme inhibitors have been shown to attenuate
adverse remodeling after acute myocardial infarction (AMI), and the same has been …