Experimental animal model systems for understanding salivary secretory disorders

JY Kim, CH An, JY Kim, JK Jung - International journal of molecular …, 2020 - mdpi.com
Salivary secretory disorders are life-disrupting pathologic conditions with a high prevalence,
especially in the geriatric population. Both patients and clinicians frequently feel helpless …

Current cell models for bioengineering a salivary gland: a mini‐review of emerging technologies

J Nelson, K Manzella, OJ Baker - Oral diseases, 2013 - Wiley Online Library
Oral Diseases (2013) 19, 236–244 Saliva plays a major role in maintaining oral health.
Patients afflicted with a decrease in saliva secretion (symptomatically, xerostomia) exhibit …

Comparing human and mouse salivary glands: A practice guide for salivary researchers

CL Maruyama, MM Monroe, JP Hunt… - Oral …, 2019 - Wiley Online Library
Mice are a widely utilized in vivo model for translational salivary gland research but must be
used with caution. Specifically, mouse salivary glands are similar in many ways to human …

Salivary gland bioengineering-yesterday, today, tomorrow!

J Iyer, S Pillai, JG Munguia Lopez, Y Zhang… - 2023 - digitum.um.es
Salivary glands are specialized structures developed as an extensively compact, arborized
design through classical embryogenesis, accompanied by a cascade of events channelized …

Physiology, pathology and regeneration of salivary glands

C Porcheri, TA Mitsiadis - Cells, 2019 - mdpi.com
Salivary glands are essential structures in the oral cavity. A variety of diseases, such as
cancer, autoimmune diseases, infections and physical traumas, can alter the functionality of …

Anatomy, biogenesis and regeneration of salivary glands

KV Holmberg, MP Hoffman - Saliva: secretion and functions, 2014 - karger.com
An overview of the anatomy and biogenesis of salivary glands is important in order to
understand the physiology, functions and disorders associated with saliva. A major disorder …

Salivary bioscience

DA Granger, MK Taylor - Foundations of Interdisciplinary Saliva Research …, 2020 - Springer
Thousands of investigators worldwide are actively engaged in basic, applied, and clinical
research involving salivary bioscience. Our literature search reveals that across the past two …

Salivary gland tissue engineering to attain clinical benefits: a special report

E Khan, I Farooq, A Khabeer, S Ali, MS Zafar… - Regenerative …, 2020 - Future Medicine
The salivary glands produce saliva, which helps in mediating the oral colonization of
microbes, the repair of mucosa, the remineralization of teeth, lubrication and gustation …

[HTML][HTML] Progress in salivary glands: Endocrine glands with immune functions

YF Shang, YY Shen, MC Zhang, MC Lv… - Frontiers in …, 2023 - frontiersin.org
The production and secretion of saliva is an essential function of the salivary glands. Saliva
is a complicated liquid with different functions, including moistening, digestion …

Salivary gland development: a template for regeneration

VN Patel, MP Hoffman - Seminars in cell & developmental biology, 2014 - Elsevier
The mammalian salivary gland develops as a highly branched structure designed to
produce and secrete saliva. This review will focus on research on mouse submandibular …