Flavonols as potential antiviral drugs targeting SARS-CoV-2 proteases (3CLpro and PLpro), spike protein, RNA-dependent RNA polymerase (RdRp) and angiotensin …

C Mouffouk, S Mouffouk, S Mouffouk… - European journal of …, 2021 - Elsevier
The novel coronavirus outbreak (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) represents the actual greatest global public health crisis. The …

Flavonoids: A complementary approach to conventional therapy of COVID-19?

J Solnier, JP Fladerer - Phytochemistry Reviews, 2021 - Springer
COVID-19, the highly contagious novel disease caused by SARS-CoV-2, has become a
major international concern as it has spread quickly all over the globe. However, scientific …

Potential bioactive glycosylated flavonoids as SARS-CoV-2 main protease inhibitors: A molecular docking and simulation studies

SA Cherrak, H Merzouk, N Mokhtari-Soulimane - Plos one, 2020 - journals.plos.org
A novel coronavirus responsible of acute respiratory infection closely related to SARS-CoV
has recently emerged. So far there is no consensus for drug treatment to stop the spread of …

Perspectives on plant flavonoid quercetin-based drugs for novel SARS-CoV-2

M Saakre, D Mathew, V Ravisankar - … -Suef University Journal of Basic and …, 2021 - Springer
Background The world pandemic COVID-19 caused by SARS-CoV-2 is currently claiming
thousands of lives. Flavonoids abundantly present in the fruits and vegetables, especially …

Commercially available flavonols are better SARS-CoV-2 inhibitors than isoflavone and flavones

OA Chaves, N Fintelman-Rodrigues, X Wang… - Viruses, 2022 - mdpi.com
Despite the fast development of vaccines, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is still circulating and generating variants of concern (VoC) that escape the …

Flavonoids as promising antiviral agents against SARS-CoV-2 infection: a mechanistic review

MA Khazeei Tabari, A Iranpanah, R Bahramsoltani… - Molecules, 2021 - mdpi.com
A newly diagnosed coronavirus in 2019 (COVID-19) has affected all human activities since
its discovery. Flavonoids commonly found in the human diet have attracted a lot of attention …

[HTML][HTML] Computational selection of flavonoid compounds as inhibitors against SARS-CoV-2 main protease, RNA-dependent RNA polymerase and spike proteins: A …

MR Rameshkumar, P Indu, N Arunagirinathan… - Saudi journal of …, 2021 - Elsevier
An outbreak of Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has been
recognized as a global health concern. Since, no specific antiviral drug is proven effective …

Promising antiviral activities of natural flavonoids against SARS-CoV-2 targets: systematic review

R Kaul, P Paul, S Kumar, D Büsselberg… - International journal of …, 2021 - mdpi.com
The ongoing COVID-19 pandemic, caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) became a globally leading public health concern over the past …

Amentoflavone derivatives significantly act towards the main protease (3CLPRO/MPRO) of SARS-CoV-2: in silico admet profiling, molecular docking, molecular …

D Dey, R Hossain, P Biswas, P Paul, MA Islam… - Molecular …, 2023 - Springer
SARS-CoV-2 is the foremost culprit of the novel coronavirus disease 2019 (nCoV-19 and/or
simply COVID-19) and poses a threat to the continued life of humans on the planet and …

Flavonoids with inhibitory activity against SARS-CoV-2 3CLpro

S Jo, S Kim, DY Kim, MS Kim… - Journal of Enzyme …, 2020 - Taylor & Francis
Abstract Coronavirus disease 2019 (COVID-19) has been a pandemic disease of which the
termination is not yet predictable. Currently, researches to develop vaccines and treatments …