Antioxidants and nanotechnology: promises and limits of potentially disruptive approaches in the treatment of central nervous system diseases
C Martinelli, C Pucci, M Battaglini… - Advanced …, 2020 - Wiley Online Library
Many central nervous system (CNS) diseases are still incurable and only symptomatic
treatments are available. Oxidative stress is suggested to be a common hallmark, being able …
treatments are available. Oxidative stress is suggested to be a common hallmark, being able …
Antioxidant therapy in oxidative stress-induced neurodegenerative diseases: Role of nanoparticle-based drug delivery systems in clinical translation
Free radicals are formed as a part of normal metabolic activities but are neutralized by the
endogenous antioxidants present in cells/tissue, thus maintaining the redox balance. This …
endogenous antioxidants present in cells/tissue, thus maintaining the redox balance. This …
Nano-antioxidants: An emerging strategy for intervention against neurodegenerative conditions
Oxidative stress has for long been linked to the neuronal cell death in many
neurodegenerative conditions. Conventional antioxidant therapies have been less effective …
neurodegenerative conditions. Conventional antioxidant therapies have been less effective …
Antioxidant strategies in protection against neurodegenerative disorders
The most common neurodegenerative diseases include Alzheimer's disease, Parkinson's
disease and stroke; they are devastating clinical problems which lack effective treatments …
disease and stroke; they are devastating clinical problems which lack effective treatments …
The discovery and development of new potential antioxidant agents for the treatment of neurodegenerative diseases
Introduction: Several neurodegenerative disorders (NDs) including Alzheimer's and
Huntington's diseases have had associations with the oxidative process and free radical …
Huntington's diseases have had associations with the oxidative process and free radical …
Nanomaterials alleviating redox stress in neurological diseases: mechanisms and applications
Y Jiang, Y Kang, J Liu, S Yin, Z Huang… - Journal of …, 2022 - Springer
Overproduced reactive oxygen and reactive nitrogen species (RONS) in the brain are
involved in the pathogenesis of several neurological diseases, such as Alzheimer's disease …
involved in the pathogenesis of several neurological diseases, such as Alzheimer's disease …
The role of nanomaterials in stroke treatment: Targeting oxidative stress
G Song, M Zhao, H Chen, C Lenahan… - Oxidative Medicine …, 2021 - Wiley Online Library
Stroke has a high rate of morbidity and disability, which seriously endangers human health.
In stroke, oxidative stress leads to further damage to the brain tissue. Therefore, treatment for …
In stroke, oxidative stress leads to further damage to the brain tissue. Therefore, treatment for …
Antioxidant for neurological diseases and neurotrauma and bioengineering approaches
Antioxidants are a class of molecules with an innate affinity to neutralize reactive oxygen
species (ROS), which are known to cause oxidative stress. Oxidative stress has been …
species (ROS), which are known to cause oxidative stress. Oxidative stress has been …
Antioxidative nanomaterials and biomedical applications
Y Liu, J Shi - Nano Today, 2019 - Elsevier
Highlights•This review article offers an in-depth overview of significant advances in the field
of antioxidative nanotechnology.•The pathology and molecular mechanisms of oxidative …
of antioxidative nanotechnology.•The pathology and molecular mechanisms of oxidative …
Antioxidants as treatment for neurodegenerative disorders
B Moosmann, C Behl - Expert opinion on investigational drugs, 2002 - Taylor & Francis
Oxidative stress is a ubiquitously observed hallmark of neurodegenerative disorders.
Neuronal cell dysfunction and cell death due to oxidative stress may causally contribute to …
Neuronal cell dysfunction and cell death due to oxidative stress may causally contribute to …