Autonomous aldosterone overproduction represents the underlying condition of 5–10% of
patients with arterial hypertension and carries a significant burden of mortality and morbidity …

Approaching the fiftieth year since its original description, primary aldosteronism is now
thought to be the commonest potentially curable and specifically treatable form of …

Primary aldosteronism (PA) secondary to excessive and/or autonomous aldosterone
secretion from the renin–angiotensin system accounts for∼ 10% of cases of hypertension …

It is now widely recognized that primary aldosteronism (PA) is much more common than
previously thought, accounting for up to 5–10% of hypertensives, and that aldosterone …

Primary aldosteronism is much more common than previously thought. The high prevalence
of primary aldosteronism, the damage this condition does to the heart, blood vessels and …

Background Primary aldosteronism is much more common than previously held; it implies
an excessive organ damage to the heart, vessels and kidney, which translates into an …

Primary aldosteronism is a common cause of hypertension and is a risk factor for
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …

Primary aldosteronism is caused by bilateral idiopathic hyperplasia in approximately two-
thirds of cases and aldosterone-producing adenoma in one-third. Most patients with primary …

Primary aldosteronism is considered the commonest cause of secondary hypertension. In
affected individuals, aldosterone is produced in an at least partially autonomous fashion in …

Primary aldosteronism used to be considered a rare cause of secondary hypertension.
However, accruing evidence indicates that primary aldosteronism is more common than …