Preclinical models of human disease provide powerful tools for therapeutic discovery but
have limitations. This problem is especially apparent in the field of acute kidney injury (AKI) …

Acute kidney injury (AKI) is a common clinical condition with various causes and is
associated with increased mortality. Despite advances in supportive care, AKI increases not …

Acute kidney injury (AKI) is a heterogeneous clinical syndrome that has multiple aetiologies,
variable pathogenesis and diverse outcomes. However, these heterogeneities are not …

Renal ischemia-reperfusion leads to acute kidney injury (AKI), a major kidney disease
associated with an increasing prevalence and high mortality rates. A variety of experimental …

In recent years, there have been numerous advances in understanding the molecular
determinants of functional kidney injury after ischemic and/or toxic exposure. However …

Acute kidney injury (AKI) and chronic kidney disease (CKD) are worldwide public health
problems affecting millions of people and have rapidly increased in prevalence in recent …

Acute kidney injury (AKI) is common (especially during critical illness), increasing in
incidence, and is associated with considerable morbidity and mortality. The Risk, Injury …

Acute kidney injury (AKI) is a global public health concern associated with high morbidity,
mortality, and healthcare costs. Other than dialysis, no therapeutic interventions reliably …

Acute kidney injury (AKI) remains a complex clinical problem associated with significant
short-term morbidity and mortality and lacking effective pharmacologic interventions …

Acute kidney injury (AKI) is the most common cause of organ dysfunction in critically ill
adults, with a single episode of AKI, regardless of stage, carrying a significant morbidity and …