Behavioral, neuroanatomical, and molecular correlates of resilience and susceptibility to maternal immune activation

FS Mueller, J Scarborough, SM Schalbetter… - Molecular …, 2021 - nature.com
Infectious or noninfectious maternal immune activation (MIA) is an environmental risk factor
for psychiatric and neurological disorders with neurodevelopmental etiologies. Whilst there …

Early or late gestational exposure to maternal immune activation alters neurodevelopmental trajectories in mice: an integrated neuroimaging, behavioral, and …

E Guma, P do Couto Bordignon, GA Devenyi… - Biological …, 2021 - Elsevier
Background Exposure to maternal immune activation (MIA) in utero is a risk factor for
neurodevelopmental disorders later in life. The impact of the gestational timing of MIA …

Maternal immune activation alters fetal brain development and enhances proliferation of neural precursor cells in rats

KJ Baines, DM Hillier, FL Haddad… - Frontiers in …, 2020 - frontiersin.org
Maternal immune activation (MIA) caused by exposure to pathogens or inflammation during
critical periods of neurodevelopment is a major risk factor for behavioral deficits and …

[HTML][HTML] Maternal immune activation transgenerationally modulates maternal care and offspring depression-like behavior

M Ronovsky, S Berger, A Zambon, SN Reisinger… - Brain, behavior, and …, 2017 - Elsevier
Gestational infection is increasingly being recognized for its involvement as causative
mechanism in severe developmental brain abnormalities and its contribution to the …

Preliminary evidence of neuropathology in nonhuman primates prenatally exposed to maternal immune activation

RK Weir, R Forghany, SEP Smith, PH Patterson… - Brain, behavior, and …, 2015 - Elsevier
Maternal infection during pregnancy increases the risk for neurodevelopmental disorders in
offspring. Rodent models have played a critical role in establishing maternal immune …

Baseline immunoreactivity before pregnancy and poly (I: C) dose combine to dictate susceptibility and resilience of offspring to maternal immune activation

ML Estes, K Prendergast, JA MacMahon… - Brain, behavior, and …, 2020 - Elsevier
Despite the potential of rodent models of maternal immune activation (MIA) to identify new
biomarkers and therapeutic interventions for a range of psychiatric disorders, current …

[HTML][HTML] Maternal immune activation in rodent models: A systematic review of neurodevelopmental changes in gene expression and epigenetic modulation in the …

RM Woods, JM Lorusso, HG Potter, JC Neill… - Neuroscience & …, 2021 - Elsevier
Maternal immune activation (mIA) during pregnancy is hypothesised to disrupt offspring
neurodevelopment and predispose offspring to neurodevelopmental disorders such as …

Maternal immune activation and related factors in the risk of offspring psychiatric disorders

F Conway, AS Brown - Frontiers in psychiatry, 2019 - frontiersin.org
Maternal immune activation (MIA) at the time of gestation has been linked to increased risk
of neurodevelopmental psychiatric disorders. Animal and human models have been used to …

Neurodevelopmental resilience and susceptibility to maternal immune activation

U Meyer - Trends in neurosciences, 2019 - cell.com
Maternal immune activation (MIA), be it triggered by infectious or noninfectious stimuli, is
implicated in various psychiatric and neurological disorders with developmental etiologies …

Maternal immune activation, central nervous system development and behavioral phenotypes

E Minakova, BB Warner - Birth defects research, 2018 - Wiley Online Library
Maternal immune activation (MIA) refers to a maternal immune system triggered by
infectious or infectious‐like stimuli. A cascade of cytokines and immunologic alterations are …