Autism spectrum disorder (ASD) has emerged as one of the most prevalent and poorly
understood disorders of our time. The etiology of autism currently remains poorly …

Prenatal exposure to infectious and/or inflammatory insults is increasingly recognized to
contribute to the etiology of psychiatric disorders with neurodevelopmental components …

Despite the potential of rodent models of maternal immune activation (MIA) to identify new
biomarkers and therapeutic interventions for a range of psychiatric disorders, current …

Schizophrenia is a complex neuropsychiatric disorder, influenced by a combined action of
genes and environmental factors. The neurodevelopmental origin is one of the most widely …

Maternal immune activation (MIA) disrupts the central innate immune system during a critical
neurodevelopmental period. Microglia are primary innate immune cells in the brain although …

Background Maternal immune activation (MIA) is a risk factor for neurodevelopmental
disorders such as autism and schizophrenia, as well as seizure development. The amygdala …

Activation of the maternal innate immune system, termed “maternal immune activation”(MIA),
represents a common environmental risk factor for schizophrenia. Whereas evidence …

Gestational infection constitutes a risk factor for the occurrence of psychiatric disorders in the
offspring. Activation of the maternal immune system (MIA) with subsequent impact on the …

Maternal infection during pregnancy increases the risk for neurodevelopmental disorders in
offspring. Rodent models have played a critical role in establishing maternal immune …

Maternal immune activation (MIA) during critical windows of gestation is correlated with long-
term neurodevelopmental deficits in the offspring, including increased risk for autism …