The house mouse (Mus musculus) is an exceptional model system, combining genetic
tractability with close evolutionary affinity to humans,. Mouse gestation lasts only 3 weeks …

The house mouse, Mus musculus, is an exceptional model system, combining genetic
tractability with close homology to human biology. Gestation in mouse development lasts …

During post-implantation development of the mouse embryo, descendants of the inner cell
mass in the early epiblast transit from the naive to primed pluripotent state. Concurrently …

Ontogeny describes the emergence of complex multicellular organisms from single
totipotent cells. This field is particularly challenging in mammals, owing to the indeterminate …

Mammalian organogenesis is a remarkable process. Within a short timeframe, the cells of
the three germ layers transform into an embryo that includes most of the major internal and …

Traditionally, the mouse has been the favoured vertebrate model for biomedical research,
due to its experimental and genetic tractability. However, non-rodent embryological studies …

During early human pregnancy the uterine mucosa transforms into the decidua, into which
the fetal placenta implants and where placental trophoblast cells intermingle and …

Mammalian embryogenesis is characterized by rapid cellular proliferation and
diversification. Within a few weeks, a single-cell zygote gives rise to millions of cells …

Cellular dynamics and fate decision in early human embryogenesis remain largely unknown
owing to the challenges of performing studies in human embryos. Here, we explored whole …

Scientists have used human stem cells to mimic the earliest stage yet of embryo growth.
Multiple research groups independently report that they have grown balls of cells that look …