Effects of empagliflozin on renal sodium and glucose handling in patients with acute heart failure

EM Boorsma, JC Beusekamp… - European journal of …, 2021 - Wiley Online Library
Aims Sodium–glucose co‐transporter 2 (SGLT2) inhibitors improve clinical outcome in
patients with heart failure (HF), but the mechanisms behind their beneficial effects are not yet …

Renal effects of empagliflozin in patients hospitalized for acute heart failure: from the EMPULSE trial

AA Voors, K Damman, JR Teerlink… - European journal of …, 2022 - Wiley Online Library
Aim The sodium–glucose cotransporter 2 (SGLT2) inhibitor empagliflozin improved clinical
outcomes in patients hospitalized for acute heart failure. In patients with chronic heart failure …

Randomized, double‐blind, placebo‐controlled, multicentre pilot study on the effects of empagliflozin on clinical outcomes in patients with acute decompensated heart …

K Damman, JC Beusekamp… - European journal of …, 2020 - Wiley Online Library
Aims Inhibition of sodium–glucose co‐transporter 2 (SGLT2) reduces the risk of death and
heart failure (HF) admissions in patients with chronic HF. However, safety and clinical …

Effects of early empagliflozin initiation on diuresis and kidney function in patients with acute decompensated heart failure (EMPAG-HF)

PC Schulze, J Bogoviku, J Westphal, P Aftanski… - Circulation, 2022 - Am Heart Assoc
Background: Effective diuretic regimens using loop diuretics in patients with acute
decompensated heart failure are often limited by the development of worsening kidney …

Empagliflozin in heart failure: diuretic and cardiorenal effects

M Griffin, VS Rao, J Ivey-Miranda, J Fleming… - Circulation, 2020 - Am Heart Assoc
Background: Sodium-glucose cotransporter-2 inhibitors improve heart failure–related
outcomes. The mechanisms underlying these benefits are not well understood, but diuretic …

Sodium–glucose co‐transporter 2 inhibition in patients hospitalized for acute decompensated heart failure: rationale for and design of the EMPULSE trial

J Tromp, P Ponikowski, A Salsali… - European journal of …, 2021 - Wiley Online Library
Aims Treatment with sodium–glucose co‐transporter 2 (SGLT2) inhibitors improves
outcomes in patients with chronic heart failure (HF) with reduced ejection fraction. There is …

[HTML][HTML] Cardiovascular and renal outcomes with empagliflozin in heart failure

M Packer, SD Anker, J Butler, G Filippatos… - … England Journal of …, 2020 - Mass Medical Soc
Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of
hospitalization for heart failure in patients regardless of the presence or absence of …

Effect of empagliflozin as an add-on therapy on decongestion and renal function in patients with diabetes hospitalized for acute decompensated heart failure: a …

S Tamaki, T Yamada, T Watanabe, T Morita… - Circulation: Heart …, 2021 - Am Heart Assoc
Background: Empagliflozin reduces the risk of hospitalization for heart failure in patients with
type 2 diabetes and cardiovascular disease. We sought to elucidate the effect of …

Renal and cardiovascular effects of SGLT2 inhibition in combination with loop diuretics in patients with type 2 diabetes and chronic heart failure: the RECEDE-CHF …

NA Mordi, IR Mordi, JS Singh, RJ McCrimmon… - Circulation, 2020 - Am Heart Assoc
Background: SGLT2 (sodium-glucose cotransporter-2) inhibitors improve heart failure–
associated outcomes in patients with type 2 diabetes. In patients with heart failure, SGLT2 …

Effect of empagliflozin on cardiovascular and renal outcomes in patients with heart failure by baseline diabetes status: results from the EMPEROR-reduced trial

SD Anker, J Butler, G Filippatos, MS Khan, N Marx… - Circulation, 2021 - Am Heart Assoc
Background: Sodium-glucose cotransporter 2 inhibitors improve outcomes in patients with
heart failure with reduced ejection fraction, but additional information is needed about …