CGmapTools improves the precision of heterozygous SNV calls and supports allele-specific methylation detection and visualization in bisulfite-sequencing data

W Guo, P Zhu, M Pellegrini, MQ Zhang, X Wang… - …, 2018 - academic.oup.com
Motivation DNA methylation is important for gene silencing and imprinting in both plants and
animals. Recent advances in bisulfite sequencing allow detection of single nucleotide …

Detection of DNA methylation by whole-genome bisulfite sequencing

Q Li, PJ Hermanson, NM Springer - Maize: Methods and Protocols, 2018 - Springer
DNA methylation plays an important role in the regulation of the expression of transposons
and genes. Various methods have been developed to assay DNA methylation levels …

Bis-SNP: combined DNA methylation and SNP calling for Bisulfite-seq data

Y Liu, KD Siegmund, PW Laird, BP Berman - Genome biology, 2012 - Springer
Bisulfite treatment of DNA followed by high-throughput sequencing (Bisulfite-seq) is an
important method for studying DNA methylation and epigenetic gene regulation, yet current …

An integrated package for bisulfite DNA methylation data analysis with Indel-sensitive mapping

Q Zhou, JQ Lim, WK Sung, G Li - BMC bioinformatics, 2019 - Springer
Background DNA methylation plays crucial roles in most eukaryotic organisms. Bisulfite
sequencing (BS-Seq) is a sequencing approach that provides quantitative cytosine …

Kismeth: analyzer of plant methylation states through bisulfite sequencing

E Gruntman, Y Qi, RK Slotkin, T Roeder… - BMC …, 2008 - Springer
Background There is great interest in probing the temporal and spatial patterns of cytosine
methylation states in genomes of a variety of organisms. It is hoped that this will shed light …

BSmooth: from whole genome bisulfite sequencing reads to differentially methylated regions

KD Hansen, B Langmead, RA Irizarry - Genome biology, 2012 - Springer
DNA methylation is an important epigenetic modification involved in gene regulation, which
can now be measured using whole-genome bisulfite sequencing. However, cost, complexity …

[HTML][HTML] MethylExtract: high-quality methylation maps and SNV calling from whole genome bisulfite sequencing data

G Barturen, A Rueda, JL Oliver, M Hackenberg - F1000Research, 2013 - ncbi.nlm.nih.gov
Whole genome methylation profiling at a single cytosine resolution is now feasible due to
the advent of high-throughput sequencing techniques together with bisulfite treatment of the …

BS-SNPer: SNP calling in bisulfite-seq data

S Gao, D Zou, L Mao, H Liu, P Song, Y Chen… - …, 2015 - academic.oup.com
Sodium bisulfite conversion followed by sequencing (BS-Seq, such as whole genome
bisulfite sequencing or reduced representation bisulfite sequencing) has become popular …

Amplification-free whole-genome bisulfite sequencing by post-bisulfite adaptor tagging

F Miura, Y Enomoto, R Dairiki, T Ito - Nucleic acids research, 2012 - academic.oup.com
DNA methylation plays a key role in epigenetic regulation of eukaryotic genomes. Hence the
genome-wide distribution of 5-methylcytosine, or the methylome, has been attracting intense …

swDMR: a sliding window approach to identify differentially methylated regions based on whole genome bisulfite sequencing

Z Wang, X Li, Y Jiang, Q Shao, Q Liu, BY Chen… - PloS one, 2015 - journals.plos.org
DNA methylation is a widespread epigenetic modification that plays an essential role in
gene expression through transcriptional regulation and chromatin remodeling. The …