Childhood growth hormone treatment and metabolic and cardiovascular risk in adults born small for gestational age after growth hormone cessation in the …

WJ Goedegebuure, M van der Steen… - The Lancet Child & …, 2022 - thelancet.com
Background Childhood growth hormone treatment has been associated with increased
cardiovascular mortality and morbidity in adults born small for gestational age (SGA) …

Cardiovascular risk factors and carotid intima media thickness in young adults born small for gestational age after cessation of growth hormone treatment: a 5-year …

M van der Steen, GF Kerkhof, CCJ Smeets… - The Lancet Diabetes & …, 2017 - thelancet.com
Background Growth hormone treatment reduces blood pressure and lipid concentrations.
We assessed long-term changes in blood pressure, lipid concentrations, and carotid intima …

Metabolic health of young adults who were born small for gestational age and treated with growth hormone, after cessation of growth hormone treatment: a 5-year …

M van der Steen, CCJ Smeets, GF Kerkhof… - The Lancet Diabetes & …, 2017 - thelancet.com
Background Growth hormone treatment reduces fat mass and insulin sensitivity and
increases lean body mass. Data are only available for short-term longitudinal changes after …

Body composition, blood pressure, and lipid metabolism before and during long-term growth hormone (GH) treatment in children with short stature born small for …

T Sas, P Mulder… - The Journal of Clinical …, 2000 - academic.oup.com
To assess the effects of long-term continuous GH treatment on body composition, blood
pressure (BP), and lipid metabolism in children with short stature born small for gestational …

The impact of long-term growth hormone treatment on metabolic parameters in Japanese patients with short stature born small for gestational age

AM Kappelgaard, F Kiyomi, R Horikawa… - Hormone Research in …, 2014 - karger.com
Abstract Background/Aims: An examination of the effects of up to 260 weeks of growth
hormone (GH) therapy on metabolic parameters in Japanese children born small for …

The effect of growth hormone treatment on metabolic and cardiovascular risk factors is similar in preterm and term short, small for gestational age children

SWK De Kort, RH Willemsen… - Clinical …, 2009 - Wiley Online Library
Context We previously reported that short, small for gestational age (SGA) children who
were born preterm have a lower body fat percentage and a higher blood pressure, insulin …

Effect of discontinuation of growth hormone treatment on risk factors for cardiovascular disease in adolescents born small for gestational age

Y van Pareren, P Mulder, M Houdijk… - The Journal of …, 2003 - academic.oup.com
Hyperlipidemia, diabetes mellitus type 2, and coronary heart disease have been associated
with being born small for gestational age (SGA). It has been reported that GH treatment …

Association of childhood growth hormone treatment with long-term cardiovascular morbidity

A Tidblad, M Bottai, H Kieler… - JAMA …, 2021 - jamanetwork.com
Importance Concerns about the cardiovascular safety of recombinant human growth
hormone (rhGH) treatment in childhood have recently been raised; however, long-term …

Long-term mortality after childhood growth hormone treatment: the SAGhE cohort study

L Sävendahl, R Cooke, A Tidblad… - The lancet Diabetes & …, 2020 - thelancet.com
Background Recombinant human growth hormone has been used for more than 30 years
and its indications have increased worldwide. There is concern that this treatment might …

Cardiovascular disease in former pediatric recipients of growth hormone: another look at growth hormone safety

A Grimberg - JAMA pediatrics, 2021 - jamanetwork.com
In this issue of JAMA Pediatrics, Tidblad et al1 report a Swedish nationwide cohort study of
3408 adults who had received growth hormone treatment during childhood from 1985 to …