Imaging structural and functional brain networks in temporal lobe epilepsy

BC Bernhardt, SJ Hong, A Bernasconi… - Frontiers in human …, 2013 - frontiersin.org
Early imaging studies in temporal lobe epilepsy (TLE) focused on the search for mesial
temporal sclerosis, as its surgical removal results in clinically meaningful improvement in …

Network analysis for a network disorder: the emerging role of graph theory in the study of epilepsy

BC Bernhardt, L Bonilha, DW Gross - Epilepsy & Behavior, 2015 - Elsevier
Recent years have witnessed a paradigm shift in the study and conceptualization of
epilepsy, which is increasingly understood as a network-level disorder. An emblematic case …

Evolution of functional connectivity of brain networks and their dynamic interaction in temporal lobe epilepsy

VL Morgan, B Abou-Khalil, BP Rogers - Brain connectivity, 2015 - liebertpub.com
This study presents a cross-sectional investigation of functional networks in temporal lobe
epilepsy (TLE) as they evolve over years of disease. Networks of interest were identified …

Graph theory findings in the pathophysiology of temporal lobe epilepsy

S Chiang, Z Haneef - Clinical Neurophysiology, 2014 - Elsevier
Temporal lobe epilepsy (TLE) is the most common form of adult epilepsy. Accumulating
evidence has shown that TLE is a disorder of abnormal epileptogenic networks, rather than …

Aberrant topological patterns of brain structural network in temporal lobe epilepsy

CL Yasuda, Z Chen, GC Beltramini, AC Coan… - …, 2015 - Wiley Online Library
Objective Although altered large‐scale brain network organization in patients with temporal
lobe epilepsy (TLE) has been shown using morphologic measurements such as cortical …

Presurgical connectome and postsurgical seizure control in temporal lobe epilepsy

L Bonilha, JA Helpern, R Sainju, T Nesland… - Neurology, 2013 - AAN Enterprises
Objectives: The objective of this study was to evaluate whether patients with surgically
refractory medial temporal lobe epilepsy (MTLE) exhibit a distinct pattern of structural …

Functional connectome contractions in temporal lobe epilepsy: Microstructural underpinnings and predictors of surgical outcome

S Larivière, Y Weng, R Vos de Wael, J Royer… - …, 2020 - Wiley Online Library
Objective Temporal lobe epilepsy (TLE) is the most common drug‐resistant epilepsy in
adults. Although it is commonly related to hippocampal pathology, increasing evidence …

Graph-theoretical analysis reveals disrupted small-world organization of cortical thickness correlation networks in temporal lobe epilepsy

BC Bernhardt, Z Chen, Y He, AC Evans… - Cerebral …, 2011 - academic.oup.com
Temporal lobe epilepsy (TLE) is the most common drug-resistant epilepsy in adults. As
morphometric studies have shown widespread structural damage in TLE, this condition is …

[HTML][HTML] Impaired and facilitated functional networks in temporal lobe epilepsy

L Maccotta, BJ He, AZ Snyder, LN Eisenman… - NeuroImage: Clinical, 2013 - Elsevier
How epilepsy affects brain functional networks remains poorly understood. Here we
investigated resting state functional connectivity of the temporal region in temporal lobe …

Mapping limbic network organization in temporal lobe epilepsy using morphometric correlations: insights on the relation between mesiotemporal connectivity and …

BC Bernhardt, KJ Worsley, P Besson, L Concha… - Neuroimage, 2008 - Elsevier
Temporal lobe epilepsy (TLE) is considered primarily a limbic disorder. Our purpose was to
map limbic network organization in TLE and to statistically relate it to neocortical atrophy. We …