Relationship between Hypoxia and Hypercapnia Tolerance and Life Expectancy

PP Tregub, YK Komleva, VP Kulikov… - International Journal of …, 2024 - mdpi.com
The review discusses the potential relationship between hypoxia resistance and longevity,
the influence of carbon dioxide on the mechanisms of aging of the mammalian organism …

Molecular mechanisms of Neuroprotection after the intermittent exposures of Hypercapnic Hypoxia

PP Tregub, VP Kulikov, I Ibrahimli, OF Tregub… - International Journal of …, 2024 - mdpi.com
The review introduces the stages of formation and experimental confirmation of the
hypothesis regarding the mutual potentiation of neuroprotective effects of hypoxia and …

Hypercapnic hypoxia as a potential means to extend life expectancy and improve physiological activity in mice

VP Kulikov, PP Tregub, IS Osipov, AI Trukhanov - Biogerontology, 2019 - Springer
The application of combined hypoxia and hypercapnia (hypercapnic hypoxia) during
respiratory exercises results in a maximum increase in resistance to acute hypoxia and …

Intermittent hypoxic training as an effective tool for increasing the adaptive potential, endurance and working capacity of the brain

EA Rybnikova, NN Nalivaeva, MY Zenko… - Frontiers in …, 2022 - frontiersin.org
This review is devoted to the phenomenon of intermittent hypoxic training and is aimed at
drawing the attention of researchers to the necessity of studying the mechanisms mediating …

Hypoxia as a therapeutic tool in search of healthy aging

A Camacho-Cardenosa, J Burtscher… - Frontiers in …, 2023 - frontiersin.org
Physical activity is considered one of the most powerful life-style interventions to promote
healthy ageing (Sallis, 2015). However, older adults rarely meet the recommended levels of …

[图书][B] The role of endogenous protein antioxidants in neuronal adaptation to hypobaric hypoxia

S Stroev - 2014 - trepo.tuni.fi
New knowledge about prevention of brain damage to severe hypoxia Decrease in
antioxidants during respiratory training–the paradoxical mechanism of neuronal protection A …

[DOC][DOC] Age-related peculiarities of breathing regulation and antioxidant enzymes under intermittent hypoxic training

EE Kolesnikova, OS Safronova… - J Physiol …, 2003 - researchgate.net
Introduction. It is well established that aging is associated with changes in the mechanisms
of breathing regulation, particularly, in the respiratory sensitivity to hypoxic stimuli …

Effects of hyperoxia on aging biomarkers: a systematic review

B Tessema, U Sack, Z Serebrovska, B König… - Frontiers in …, 2022 - frontiersin.org
The effects of short-term hyperoxia on age-related diseases and aging biomarkers have
been reported in animal and human experiments using different protocols; however, the …

Adaptation of human organism to hypoxia

VV Sosnowskiy, VA Pastukhova - … biological sciences series, 2017 - bio-ejournal.cdu.edu.ua
Introduction. Adaptation to hypoxia uses extensive flexible potential of organism, which is
based on structural changes in cells and tissues and can both increase the oxygen supply …

Comparative response of brain to chronic hypoxia and hyperoxia

L Terraneo, M Samaja - International journal of molecular sciences, 2017 - mdpi.com
Two antithetic terms, hypoxia and hyperoxia, ie, insufficient and excess oxygen availability
with respect to needs, are thought to trigger opposite responses in cells and tissues. This …