Efficacy of high-dose polyclonal intravenous immunoglobulin in COVID-19: A systematic review

D Focosi, M Franchini, M Tuccori, M Cruciani - Vaccines, 2022 - mdpi.com
Background: Although several therapeutic strategies have been investigated, the optimal
treatment approach for patients with coronavirus disease (COVID-19) remains to be …

Benefits of high-dose intravenous immunoglobulin on mortality in patients with severe COVID-19: An updated systematic review and meta-analysis

X Liu, Y Zhang, L Lu, X Li, Y Wu, Y Yang, T Li… - Frontiers in …, 2023 - frontiersin.org
Background The clinical benefits of high-dose intravenous immunoglobulin (IVIg) in treating
COVID-19 remained controversial. Methods We systematically searched databases up to …

Intravenous immunoglobulin (IVIg) therapy in hospitalised adult COVID‐19 patients: A systematic review and meta‐analysis

R Marcec, VM Dodig, I Radanovic… - Reviews in medical …, 2022 - Wiley Online Library
Intravenous immunoglobulin (IVIg) therapy has been suggested as a potential treatment
option for hospitalised COVID‐19 patients. The aim of this systematic review and meta …

The effect of intravenous immunoglobulins on the outcomes of patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials

CC Lai, WC Chen, CY Chen, YF Wei - Expert Review of Anti …, 2022 - Taylor & Francis
Objectives Severe-to-critical COVID-19 has been associated with exaggerated immune
responses, and anti-inflammatory agents including corticosteroid and interleukin-6 …

Efficacy of IVIG (intravenous immunoglobulin) for corona virus disease 2019 (COVID-19): A meta-analysis

H Xiang, X Cheng, Y Li, W Luo, Q Zhang… - International …, 2021 - Elsevier
Background The benefit of IVIG (Intravenous Immunoglobulin) therapy for COVID-19
remains controversial. We performed a meta-analysis to investigate the efficacy of IVIG …

[HTML][HTML] Efficacy evaluation of intravenous immunoglobulin in non-severe patients with COVID-19: A retrospective cohort study based on propensity score matching

C Huang, L Fei, W Li, W Xu, X Xie, Q Li… - International Journal of …, 2021 - Elsevier
Objectives At the present time, there is an absence of any proven effective antiviral therapy
for patients with coronavirus disease 2019 (COVID-19). The aim of this study was to assess …

Intravenous immunoglobulin treatment for patients with severe COVID-19: a retrospective multicentre study

J Liu, Y Chen, R Li, Z Wu, Q Xu, Z Li, D Annane… - Clinical Microbiology …, 2021 - Elsevier
Objectives Intravenous immunoglobulin (IVIG) is commonly used to treat severe COVID-19,
although the clinical outcome of such treatment remains unclear. This study evaluated the …

Clinical efficacy of intravenous immunoglobulin therapy in critical ill patients with COVID‐19: a multicenter retrospective cohort study

Z Shao, Y Feng, L Zhong, Q Xie, M Lei… - Clinical & …, 2020 - Wiley Online Library
Abstract Objective Coronavirus disease 2019 (COVID‐19) outbreak is a major challenge all
over the world, without acknowledged treatment. Intravenous immunoglobulin (IVIG) has …

Immunoglobulins in the treatment of COVID-19 infection: Proceed with caution!

AA Nguyen, SB Habiballah, CD Platt, RS Geha… - Clinical …, 2020 - Elsevier
The COVID-19 pandemic is one of the greatest infectious challenges in recent history.
Presently, few treatment options exist and the availability of effective vaccines is at least one …

High-dose intravenous immunoglobulin in severe coronavirus disease 2019: a multicenter retrospective study in China

W Cao, X Liu, K Hong, Z Ma, Y Zhang, L Lin… - Frontiers in …, 2021 - frontiersin.org
Background The effective treatment of coronavirus disease 2019 (COVID-19) remains
unclear. We reported successful use of high-dose intravenous immunoglobulin (IVIg) in …