Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B. 1.1. 529

T Zhou, L Wang, J Misasi, A Pegu, Y Zhang, DR Harris… - Science, 2022 - science.org
The rapid spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.
1.1. 529 (Omicron) variant and its resistance to neutralization by vaccinee and convalescent …

Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants

L Wang, T Zhou, Y Zhang, ES Yang, CA Schramm… - Science, 2021 - science.org
INTRODUCTION Worldwide appearance of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) variants of concern (VOCs) with increased transmissibility and resistance to …

Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain

KG Nabel, SA Clark, S Shankar, J Pan, LE Clark… - Science, 2021 - science.org
Many studies have examined the impact of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) variants on neutralizing antibody activity after they have become dominant …

Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants

M Yuan, D Huang, CCD Lee, NC Wu, AM Jackson… - Science, 2021 - science.org
Neutralizing antibodies (nAbs) elicited against the receptor binding site (RBS) of the spike
protein of wild-type severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are …

[HTML][HTML] Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

Y Cao, J Wang, F Jian, T Xiao, W Song, A Yisimayi… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 B. 1.1. 529 (Omicron) variant contains 15 mutations of the
receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies …

[HTML][HTML] An infectious SARS-CoV-2 B. 1.1. 529 Omicron virus escapes neutralization by therapeutic monoclonal antibodies

LA VanBlargan, JM Errico, PJ Halfmann, SJ Zost… - Nature medicine, 2022 - nature.com
The emergence of the highly transmissible B. 1.1. 529 Omicron variant of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is concerning for antibody …

Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants

Y Cai, J Zhang, T Xiao, CL Lavine, S Rawson, H Peng… - Science, 2021 - science.org
Several fast-spreading variants of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) have become the dominant circulating strains in the COVID-19 pandemic. We report …

[HTML][HTML] Structures of SARS-CoV-2 B. 1.351 neutralizing antibodies provide insights into cocktail design against concerning variants

S Du, P Liu, Z Zhang, T Xiao, A Yasimayi, W Huang… - Cell research, 2021 - nature.com
Dear Editor, The spread of the SARS-CoV-2 variants, especially the global variants of
concern (VOCs), could seriously dampen our efforts to tackle the COVID-19 pandemic. The …

[HTML][HTML] Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies

RE Chen, X Zhang, JB Case, ES Winkler, Y Liu… - Nature medicine, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the global
COVID-19 pandemic. Rapidly spreading SARS-CoV-2 variants may jeopardize newly …

Structural basis of a shared antibody response to SARS-CoV-2

M Yuan, H Liu, NC Wu, CCD Lee, X Zhu, F Zhao… - Science, 2020 - science.org
Molecular understanding of neutralizing antibody responses to severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) could accelerate vaccine design and drug …