Serving as the basis of cell life, interactions between nucleic acids and proteins play
essential roles in fundamental cellular processes. Aptamers are unique single-stranded …

Disease-related biomarkers are objectively measurable molecular signatures of
physiological status that can serve as disease indicators or drug targets in clinical diagnosis …

Nucleic acid aptamers are single-stranded DNA or RNA of 20–100 nucleotides in length that
have attracted substantial scientific interest due to their ability to specifically bind to target …

Aptamers are promising therapeutic and diagnostic agents for various diseases due to their
high affinity and specificity against target proteins. Structural determination in combination …

Aptamers comprise a range of molecular recognition scaffolds that can be engineered to
bind to a legion of different proteins and other targets with excellent specificity and affinity …

Nucleic acid aptamers are an emerging class of synthetic ligands and have recently
attracted significant attention in numerous fields. One is in biosensor development. In …

Aptamers are single-stranded, synthetic oligonucleotides that fold into 3-dimensional
shapes capable of binding non-covalently with high affinity and specificity to a target …

The increasing number of potential drug target candidates has driven the development of
novel technologies designed to identify functionally important targets and enhance the …

Aptamers are small nucleic acid molecules capable of binding to a wide range of target
molecules with high affinity and specificity. They have been developed and widely used not …

Nucleic acid aptamers are molecules that bind to their ligands with high affinity and
specificity. Unlike other functional nucleic acids such as antisense oligonucleotides …