The presence of macrophages within the plaque is a defining hallmark of atherosclerosis.
Macrophages are exposed to various microenvironments such as oxidized lipids and …

Initiation and progression of atherosclerosis depend on local inflammation and
accumulation of lipids in the vascular wall. Although many cells are involved in the …

Macrophage accumulation within the vascular wall is a hallmark of atherosclerosis. In
atherosclerotic lesions, macrophages respond to various environmental stimuli, such as …

Macrophages are highly heterogeneous and plastic cells. They were shown to play a critical
role in all stages of atherogenesis, from the initiation to the necrotic core formation and …

Introduction• Current concepts in monocyte heterogeneity• Pro‐atherogenic role of plaque
macrophages• Anti‐atherogenic role of plaque macrophages• Macrophage heterogeneity …

Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of fatty
deposits in the inner walls of vessels. These plaques restrict blood flow and lead to …

Macrophages orchestrate the inflammatory response in inflamed tissues, and recent work
indicates that these cells can alter their phenotypes and functions accordingly in response to …

Atherosclerosis is a chronic disease starting with the entry of monocytes into the
subendothelium and the subsequent differentiation into macrophages. Macrophages are the …

Atherosclerosis is the result of a chronic inflammatory response in the arterial wall related to
uptake of low-density lipoprotein by macrophages and their subsequent transformation in …

Diversity and plasticity are hallmarks of mononuclear phagocytes, which are reflected in
plaque formation and evolution. Different monocyte subsets, which differentially contribute to …